Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AURKB | Q96GD4 | 1/20 | 0.40 |
| ▸ | AAK1 | Q2M2I8 | 6/20 | 0.40 |
| ▸ | P2RY14 | Q15391 | 4/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
| ▸ | ABL1 | P00519 | 2/20 | 0.39 |
| ▸ | BCR | P11274 | 2/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16894189 | 0.83 | CACNA1G (0.38) | AAK1FAAHKCNH2TRPV1 | |
| SCHEMBL28017384 | 0.82 | ALDH1A1 (0.38) | AAK1FAAHABL1BCRADORA3 | |
| SCHEMBL16894276 | 0.80 | AAK1 (0.36) | AAK1FAAHKCNH2TRPV1 | |
| SCHEMBL16965653 | 0.74 | KMT2A (0.40) | FAAHABL1BCRADORA3KCNH2 | |
| SCHEMBL893757 | 0.72 | HDAC1 (0.53) | P2RY14TRPV1 | |
| SCHEMBL2585523 | 0.72 | TBK1 (0.46) | — | |
| SCHEMBL18068201 | 0.71 | KDM1A (0.42) | AAK1P2RY14ADORA3 | |
| SCHEMBL16894191 | 0.71 | TRPA1 (0.47) | AAK1TRPV1 | |
| SCHEMBL17979180 | 0.69 | HDAC1 (0.43) | AAK1P2RY14ADORA3 | |
| SCHEMBL4704775 | 0.68 | CYP17A1 (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104684899-B | Substituted sulfonamide compounds | 霍夫曼-拉罗奇有限公司 | 2017-07-04 | — | — | CN | disclosed |
| CN-104684899-A | Substituted sulfonamide compounds | HOFFMANN LA ROCHE | 2015-06-03 | — | — | CN | disclosed |