Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHCY | P23526 | 8/20 | 0.78 |
| ▸ | NADK | O95544 | 1/20 | 0.78 |
| ▸ | DOT1L | Q8TEK3 | 3/20 | 0.70 |
| ▸ | DNMT3B | Q9UBC3 | 2/20 | 0.70 |
| ▸ | DNMT1 | P26358 | 2/20 | 0.70 |
| ▸ | PNMT | P11086 | 1/20 | 0.70 |
| ▸ | DPP4 | P27487 | 1/20 | 0.70 |
| ▸ | MEN1 | O00255 | 1/20 | 0.70 |
| ▸ | SLC28A1 | O00337 | 1/20 | 0.70 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.70 |
| ▸ | SLC28A2 | O43868 | 1/20 | 0.70 |
| ▸ | GAPDH | P04406 | 1/20 | 0.70 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.70 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.70 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.70 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.70 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.70 |
| ▸ | STAT6 | P42226 | 1/20 | 0.70 |
| ▸ | PI4KA | P42356 | 1/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.70 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6901126 | 0.89 | AHCY (0.78) | AHCYNADKDOT1LDNMT3BDNMT1 | |
| SCHEMBL536062 | 0.85 | AHCY (0.83) | AHCYNADKDOT1LDNMT3BDNMT1 | |
| Methylthioadenosine SCHEMBL31388809 | 0.85 | AHCY (0.83) | AHCYNADKDOT1LDNMT3BDNMT1 | |
| Methylthioadenosine SCHEMBL29361072 | 0.85 | AHCY (0.83) | AHCYNADKDOT1LDNMT3BDNMT1 | |
| Methylthioadenosine SCHEMBL890628 | 0.85 | AHCY (0.83) | AHCYNADKDOT1LDNMT3BDNMT1 | |
| Methylthioadenosine SCHEMBL11954365 | 0.85 | AHCY (0.83) | AHCYNADKDOT1LDNMT3BDNMT1 | |
| Methylthioadenosine SCHEMBL10013421 | 0.85 | AHCY (0.83) | AHCYNADKDOT1LDNMT3BDNMT1 | |
| Methylthioadenosine SCHEMBL101382 | 0.85 | AHCY (0.83) | AHCYNADKDOT1LDNMT3BDNMT1 | |
| Methylthioadenosine SCHEMBL20798030 | 0.85 | AHCY (0.83) | AHCYNADKDOT1LDNMT3BDNMT1 | |
| Methylthioadenosine SCHEMBL160358 | 0.85 | AHCY (0.83) | AHCYNADKDOT1LDNMT3BDNMT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104557358-A | Alkyl trifluoromethyl thioether compound and preparation method thereof | SHANGHAI INSITITUTE OF ORGANIC CHEMISTRY CHINESE ACADEMY OF SCIENCES | 2015-04-29 | — | — | CN | disclosed |