Methylthioadenosine

Methylthioadenosine

SCHEMBL31388809

CSC[C@H]1O[C@H](n2cnc3c(N)ncnc32)[C@H](O)[C@@H]1O

nearest known ligand 0.83

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AHCY P23526 7/20 0.83
NADK O95544 1/20 0.83
DOT1L Q8TEK3 3/20 0.74
DNMT3B Q9UBC3 2/20 0.74
ADORA3 P0DMS8 2/20 0.74
PNMT P11086 1/20 0.74
DNMT1 P26358 1/20 0.74
DPP4 P27487 1/20 0.74
MEN1 O00255 1/20 0.74
SLC28A1 O00337 1/20 0.74
MAP3K7 O43318 1/20 0.74
SLC28A2 O43868 1/20 0.74
GAPDH P04406 1/20 0.74
MAPK1 P28482 1/20 0.74
ADORA2A P29274 1/20 0.74
ADORA2B P29275 1/20 0.74
ADORA1 P30542 1/20 0.74
STAT6 P42226 1/20 0.74
PI4KA P42356 1/20 0.74
KMT2A Q03164 1/20 0.74

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methylthioadenosine SCHEMBL29439558 1.00 AHCY (0.83) AHCYNADKDOT1LDNMT3BADORA3
Methylthioadenosine SCHEMBL20798030 1.00 AHCY (0.83) AHCYNADKDOT1LDNMT3BADORA3
Methylthioadenosine SCHEMBL160358 1.00 AHCY (0.83) AHCYNADKDOT1LDNMT3BADORA3
Methylthioadenosine SCHEMBL29361072 1.00 AHCY (0.83) AHCYNADKDOT1LDNMT3BADORA3
Methylthioadenosine SCHEMBL890628 1.00 AHCY (0.83) AHCYNADKDOT1LDNMT3BADORA3
Methylthioadenosine SCHEMBL11954365 1.00 AHCY (0.83) AHCYNADKDOT1LDNMT3BADORA3
Methylthioadenosine SCHEMBL10013421 1.00 AHCY (0.83) AHCYNADKDOT1LDNMT3BADORA3
Methylthioadenosine SCHEMBL101382 1.00 AHCY (0.83) AHCYNADKDOT1LDNMT3BADORA3
Methylthioadenosine SCHEMBL7124285 0.95 DOT1L (0.78) AHCYNADKDOT1LDNMT3BPNMT
Methylthioadenosine SCHEMBL20817193 0.91 AHCY (0.70) AHCYNADKDOT1LDNMT3BADORA3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119555822-A Urine metabolism marker composition for diagnosis of cancer seeds of pan-cancer, screening method and application 哈尔滨脉图精准技术有限公司 2025-03-04 CN claimed
CN-119555822-A Urine metabolism marker composition for diagnosis of cancer seeds of pan-cancer, screening method and application 哈尔滨脉图精准技术有限公司 2025-03-04 CN disclosed