Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIPE | Q05469 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 5/20 | 0.45 |
| ▸ | KIF11 | P52732 | 1/20 | 0.43 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.40 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.40 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | MMP9 | P14780 | 1/20 | 0.40 |
| ▸ | MMP13 | P45452 | 1/20 | 0.40 |
| ▸ | MMP14 | P50281 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28018948 | 0.84 | KMT2A (0.52) | LIPERAB9AAKR1C3CYP1A2CYP2C9 | |
| SCHEMBL5652083 | 0.75 | LIPE (0.74) | LIPERAB9AAKR1C3CYP1A2CYP2C9 | |
| SCHEMBL3822896 | 0.73 | L3MBTL1 (0.41) | RAB9ASMN1; SMN2LMNAHPGDALDH1A1 | |
| SCHEMBL16463810 | 0.72 | TSHR (0.43) | LIPESMN1; SMN2ALDH1A1KDM4EKMT2A | |
| SCHEMBL4472090 | 0.71 | MAPT (0.55) | RAB9AEPHX2SMN1; SMN2HPGDALDH1A1 | |
| SCHEMBL12520685 | 0.70 | PDE10A (0.43) | AKR1C3 | |
| SCHEMBL24361155 | 0.70 | KIF11 (0.58) | EPHX2KIF11ALDH1A1 | |
| SCHEMBL9595594 | 0.70 | LIPG (0.52) | LIPEEPHX2KIF11MMP2MMP13 | |
| SCHEMBL3420665 | 0.69 | KIF11 (0.56) | KIF11CYP2C19HPGDALDH1A1KDM4E | |
| SCHEMBL6912783 | 0.69 | KIF11 (0.66) | EPHX2KIF11HPGDALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104703973-A | Substituted phenyl carbamate compounds | HOFFMANN LA ROCHE | 2015-06-10 | — | — | CN | disclosed |