SCHEMBL28018587

SCHEMBL28018587

CCOP(OCC)c1ccccc1.[Ni]

nearest known ligand 0.38

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
LTA4H P09960 1/20 0.35
TP53 P04637 1/20 0.35
RELA Q04206 1/20 0.32
NPSR1 Q6W5P4 1/20 0.32
ESR1 P03372 2/20 0.32
ESR2 Q92731 2/20 0.32
KCNN4 O15554 1/20 0.32
TSHR P16473 3/20 0.32
L3MBTL1 Q9Y468 2/20 0.31
KCNH2 Q12809 1/20 0.31
GLA P06280 1/20 0.31
ALDH1A1 P00352 3/20 0.31
HSD17B10 Q99714 1/20 0.31
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL911476 0.98 CYP3A4 (0.39) CYP3A4TDP1LTA4HTP53RELA
SCHEMBL11209353 0.91 CYP3A4 (0.35) CYP3A4TDP1LTA4HTP53RELA
SCHEMBL10792824 0.86 CYP3A4 (0.35) CYP3A4TDP1LTA4HTP53RELA
SCHEMBL11209432 0.84 LTA4H (0.43) CYP3A4TDP1LTA4HTP53NPSR1
SCHEMBL8939051 0.83 LTA4H (0.39) CYP3A4TDP1LTA4HRELATSHR
SCHEMBL27823965 0.80 PDK2 (0.35) CYP3A4TDP1LTA4HTP53RELA
SCHEMBL4457781 0.79 LMNA (0.39) CYP3A4TDP1LTA4HTP53ALDH1A1
Pyridine SCHEMBL11205969 0.78 KDM4E (0.33) CYP3A4TDP1MEN1KMT2A
SCHEMBL8939035 0.78 SCN4A (0.37) CYP3A4NPSR1TSHRL3MBTL1KCNH2
SCHEMBL196443 0.78 CYP3A4 (0.39) CYP3A4TDP1LTA4HTP53RELA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105732850-A PROCESS FOR PRODUCING OLEFIN POLYMER 住友化学株式会社 2016-07-06 CN disclosed
CN-104628903-A Method for producing olefin polymer SUMITOMO CHEMICAL CO 2015-05-20 CN disclosed