Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN4A | P35499 | 10/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | SCN8A | Q9UQD0 | 3/20 | 0.34 |
| ▸ | HTR1A | P08908 | 2/20 | 0.34 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.34 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.33 |
| ▸ | SCN1A | P35498 | 2/20 | 0.33 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8939005 | 0.86 | MAPT (0.35) | SMN1; SMN2HTR1AADRA1ALMNACYP1A2 | |
| SCHEMBL911476 | 0.80 | CYP3A4 (0.39) | CYP3A4KMT2AL3MBTL1TSHRKCNH2 | |
| SCHEMBL8939051 | 0.79 | LTA4H (0.39) | LMNACYP3A4L3MBTL1TSHR | |
| SCHEMBL28018587 | 0.78 | CYP3A4 (0.38) | CYP3A4KMT2AL3MBTL1TSHRKCNH2 | |
| SCHEMBL8939016 | 0.77 | DRD2 (0.36) | SMN1; SMN2LMNAKMT2AL3MBTL1TSHR | |
| SCHEMBL10888057 | 0.77 | SCN4A (0.37) | SCN4ASMN1; SMN2SCN8ALMNACYP1A2 | |
| SCHEMBL8939014 | 0.77 | ACHE (0.42) | LMNAKMT2AL3MBTL1HTTGAA | |
| SCHEMBL8939008 | 0.76 | L3MBTL1 (0.38) | SMN1; SMN2LMNANFKB1KMT2AL3MBTL1 | |
| SCHEMBL8939007 | 0.76 | MAPT (0.38) | SMN1; SMN2ADRA1ALMNACYP1A2KMT2A | |
| SCHEMBL10792824 | 0.75 | CYP3A4 (0.35) | CYP3A4TSHRNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5498741-A | Alkyl aryl arylphosphonites, process for the preparation thereof and use thereof | HOECHST AKTIENGESELLSCHAFT (DE) | 1996-03-12 | — | — | US | disclosed |