Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | LTA4H | P09960 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | RELA | Q04206 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | ESR1 | P03372 | 1/20 | 0.30 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.30 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.30 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL911476 | 0.93 | CYP3A4 (0.39) | CYP3A4TDP1LTA4HTP53RELA | |
| SCHEMBL28018587 | 0.91 | CYP3A4 (0.38) | CYP3A4TDP1LTA4HTP53RELA | |
| SCHEMBL10792824 | 0.83 | CYP3A4 (0.35) | CYP3A4TDP1LTA4HTP53RELA | |
| SCHEMBL11209432 | 0.80 | LTA4H (0.43) | CYP3A4TDP1LTA4HTP53NPSR1 | |
| SCHEMBL8939051 | 0.79 | LTA4H (0.39) | CYP3A4TDP1LTA4HRELATSHR | |
| SCHEMBL27823965 | 0.76 | PDK2 (0.35) | CYP3A4TDP1LTA4HTP53SMN1; SMN2 | |
| SCHEMBL8939047 | 0.76 | SCN4A (0.35) | CYP3A4TDP1LTA4HTSHR | |
| SCHEMBL11423935 | 0.76 | CYP3A4 (0.36) | CYP3A4TDP1LTA4HTP53RELA | |
| SCHEMBL4457781 | 0.76 | LMNA (0.39) | CYP3A4TDP1LTA4HTP53SMN1; SMN2 | |
| SCHEMBL11208304 | 0.76 | LMNA (0.36) | CYP3A4TDP1SMN1; SMN2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0003897-B1 | PHOSPHINEGOLD(I)SALTS, PROCESS FOR THEIR PREPARATION AND COMPOSITIONS CONTAINING THEM | SMITHKLINE BECKMAN CORPORATION (US) | 1983-05-25 | — | — | EP | disclosed |
| EP-0003897-A1 | Phosphinegold(I)salts, process for their preparation and compositions containing them | SMITHKLINE BECKMAN CORPORATION (US) | 1979-09-05 | — | — | EP | disclosed |
| US-4096250-A | ANTI-ARTHRITIC | SMITHKLINE CORPORATION (US) | 1978-06-20 | — | — | US | disclosed |