Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 3/20 | 0.44 |
| ▸ | CA2 | P00918 | 3/20 | 0.44 |
| ▸ | CA4 | P22748 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | CA6 | P23280 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27905600 | 0.84 | CA1 (0.39) | CA1CA2CA4TSHR | |
| SCHEMBL27888905 | 0.84 | CA1 (0.39) | CA1CA2CA4TSHR | |
| SCHEMBL28097052 | 0.79 | CHRM2 (0.30) | — | |
| SCHEMBL27737557 | 0.78 | — | — | |
| SCHEMBL27737553 | 0.78 | — | — | |
| SCHEMBL3603125 | 0.72 | CHRM2 (0.33) | — | |
| SCHEMBL27593040 | 0.72 | NR1H2 (0.37) | — | |
| SCHEMBL27593232 | 0.72 | LMNA (0.30) | — | |
| SCHEMBL27611213 | 0.72 | LMNA (0.40) | — | |
| SCHEMBL27896511 | 0.72 | HTR4 (0.36) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104619698-B | Pyrrolidin derivatives and the purposes as complement pathway regulator thereof | 诺华股份有限公司 | 2016-08-31 | — | — | CN | disclosed |
| CN-104619698-A | Pyrrolidine derivatives and their use as complement pathway modulators | NOVARTIS AG | 2015-05-13 | — | — | CN | disclosed |