SCHEMBL28019010

SCHEMBL28019010

CCOC(OCC)[SiH2]c1ccccc1C

nearest known ligand 0.34

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.34
TSHR P16473 2/20 0.33
ACHE P22303 1/20 0.33
ESR1 P03372 1/20 0.32
FFAR1 O14842 2/20 0.31
TDP1 Q9NUW8 1/20 0.31
ALDH1A1 P00352 1/20 0.30
LMNA P02545 1/20 0.30
ALOX12 P18054 1/20 0.30
HTT P42858 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27812022 0.79 ALDH1A1 (0.41) L3MBTL1TDP1ALDH1A1KMT2A
SCHEMBL6748996 0.77 ALDH1A1 (0.32) L3MBTL1ALDH1A1
SCHEMBL29434643 0.75 ALDH1A1 (0.33) L3MBTL1ALDH1A1
SCHEMBL4901356 0.75 ALDH1A1 (0.33) L3MBTL1ALDH1A1
SCHEMBL23493440 0.74 TSHR (0.33) L3MBTL1TSHR
SCHEMBL29434590 0.74 TSHR (0.33) L3MBTL1TSHR
SCHEMBL208072 0.74 L3MBTL1 (0.41) L3MBTL1LMNAHTTKMT2A
SCHEMBL6746797 0.72 NQO1 (0.33) ALDH1A1
SCHEMBL23040280 0.71 KCNJ11 (0.34) L3MBTL1ALDH1A1LMNAHTTKMT2A
SCHEMBL707975 0.70 THRB (0.35) L3MBTL1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102898456-B O-benzyldiethoxymethylsilane and preparation method thereof UNIV HANGZHOU NORMAL 2015-06-17 CN claimed
CN-102898456-B O-benzyldiethoxymethylsilane and preparation method thereof UNIV HANGZHOU NORMAL 2015-06-17 CN disclosed
CN-102898456-B O-benzyldiethoxymethylsilane and preparation method thereof UNIV HANGZHOU NORMAL 2015-06-17 CN disclosed