SCHEMBL23040280

SCHEMBL23040280

CCOC(OCC)[SiH2]c1ccccc1C(O)(C(F)(F)F)C(F)(F)F

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KCNJ11 Q14654 7/20 0.34
ABCC9 O60706 3/20 0.34
ABCC8 Q09428 3/20 0.34
KCNJ8 Q15842 3/20 0.34
MLYCD O95822 1/20 0.33
KDM4E B2RXH2 3/20 0.33
MEN1 O00255 2/20 0.33
MAPT P10636 2/20 0.33
KMT2A Q03164 2/20 0.33
LMNA P02545 1/20 0.33
MAPK1 P28482 1/20 0.33
HTT P42858 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
PGR P06401 1/20 0.32
NR1H2 P55055 5/20 0.32
NR1H3 Q13133 5/20 0.32
RORC P51449 2/20 0.32
ALDH1A1 P00352 1/20 0.32
GLA P06280 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23040283 0.74 MEN1 (0.38) KCNJ11ABCC9ABCC8KCNJ8KDM4E
SCHEMBL23040261 0.73 NR1H2 (0.47) MLYCDLMNASMN1; SMN2NR1H2NR1H3
SCHEMBL23040278 0.71 RORC (0.43) MEN1KMT2ALMNAMAPK1PGR
SCHEMBL28019010 0.71 L3MBTL1 (0.34) KMT2ALMNAHTTALDH1A1L3MBTL1
SCHEMBL27812022 0.69 ALDH1A1 (0.41) KDM4EMEN1MAPTKMT2AMAPK1
SCHEMBL29434590 0.68 TSHR (0.33) L3MBTL1
SCHEMBL23493440 0.68 TSHR (0.33) L3MBTL1
SCHEMBL6748996 0.67 ALDH1A1 (0.32) ALDH1A1HPGDHSD17B10L3MBTL1
SCHEMBL2582219 0.67 MEN1 (0.52) KCNJ11ABCC9ABCC8KCNJ8KDM4E
SCHEMBL4901356 0.66 ALDH1A1 (0.33) ALDH1A1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113166548-A Resin composition, photosensitive resin composition, cured film, method for producing cured film, patterned cured film, and method for producing patterned cured film 中央硝子株式会社 2021-07-23 CN disclosed
US-20210061827-A1 Silicon Compound Containing Hexafluoroisopropanol Group, and Method for Producing Same CENTRAL GLASS COMPANY, LIMITED (JP) 2021-03-04 US disclosed
CN-111819183-A Silicon compound containing hexafluoroisopropanol group and method for producing same 中央硝子株式会社 2020-10-23 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210061827-A1 Silicon Compound Containing Hexafluoroisopropanol Group, and Method for Producing Same FOS, FUBP3, SF3A3 KCNJ11 2470/4885ABCC9 4047/4885ABCC8 4073/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.