SCHEMBL28019281

SCHEMBL28019281

OC1CC(Br)Oc2ccccc21

nearest known ligand 0.41

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
MAOB P27338 2/20 0.41
MAOA P21397 1/20 0.41
ADORA3 P0DMS8 1/20 0.35
AR P10275 1/20 0.35
HSD11B1 P28845 1/20 0.35
AKR1C3 P42330 1/20 0.35
GUSB P08236 4/20 0.33
ESR1 P03372 1/20 0.33
ESR2 Q92731 1/20 0.33
LTB4R Q15722 1/20 0.33
LTB4R2 Q9NPC1 1/20 0.33
ATM Q13315 1/20 0.32
ABCB1 P08183 4/20 0.31
PTPN1 P18031 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31015947 0.77 ABCB1 (0.37) MAOBMAOAADORA3ARHSD11B1
SCHEMBL10764252 0.77 MAOA (0.41) MAOBMAOAGUSBESR1ESR2
SCHEMBL6620764 0.77 POLB (0.43) MAOBMAOAGUSBESR1ESR2
Hydrochloric Acid SCHEMBL27510735 0.76 POLB (0.42) MAOBMAOAGUSBESR1ESR2
SCHEMBL380283 0.74 CYP19A1 (0.45) MAOBMAOAADORA3ARHSD11B1
SCHEMBL1267388 0.74 CYP19A1 (0.45) MAOBMAOAADORA3ARHSD11B1
SCHEMBL30064231 0.74 CYP19A1 (0.45) MAOBMAOAADORA3ARHSD11B1
SCHEMBL24496706 0.73 SMN1; SMN2 (0.39) MAOBMAOAATMABCB1
SCHEMBL6746093 0.73 HTR2C (0.40) MAOBMAOA
SCHEMBL6327386 0.73 SMN1; SMN2 (0.39) MAOBMAOAATMABCB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104692987-B Cheap and efficient synthesis method of halogenated alcohols and derivatives thereof 北京大学 2017-05-17 CN disclosed
CN-104692987-A Cheap and efficient synthesis method of halogenated alcohols and derivatives thereof UNIV BEIJING 2015-06-10 CN disclosed