Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYR | P14679 | 3/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.34 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.34 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.34 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.32 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | MIF | P14174 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.31 |
| ▸ | THRA | P10827 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2805269 | 0.88 | ADRA2A (0.36) | TYRADRA2AADRA2BADRA2CADRB3 | |
| SCHEMBL9150470 | 0.81 | ADRA2A (0.38) | TYRADRA2AADRA2BADRA2CADRB3 | |
| SCHEMBL11079761 | 0.79 | HTT (0.38) | TYRALOX15HTT | |
| SCHEMBL11158917 | 0.76 | TYR (0.49) | TYRADRA2AADRA2BADRA2CADRB3 | |
| SCHEMBL9150253 | 0.71 | CYP3A4 (0.42) | TYRADRA2AADRA2BADRA2CADRB3 | |
| SCHEMBL2783189 | 0.71 | CA12 (0.43) | HTT | |
| SCHEMBL2987382 | 0.70 | ADRA2A (0.43) | TYRADRA2AADRA2BADRA2CNR1I2 | |
| SCHEMBL2784302 | 0.70 | MGLL (0.42) | — | |
| SCHEMBL419569 | 0.69 | TYR (0.47) | TYRADRA2AADRA2BADRA2CADRB3 | |
| SCHEMBL11095669 | 0.69 | TYR (0.47) | TYRADRA2AADRA2BADRA2CADRB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010128038-A1 | HYDROQUINONE DERIVATIVES | AXOGLIA THERAPEUTICS S.A. (LU) | 2010-11-11 | — | — | WO | disclosed |