Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 2/20 | 0.38 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.38 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.38 |
| ▸ | TYR | P14679 | 4/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | MIF | P14174 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | THRA | P10827 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.32 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.32 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2805269 | 0.93 | ADRA2A (0.36) | ADRA2AADRA2BADRA2CTYRLMNA | |
| SCHEMBL9150253 | 0.82 | CYP3A4 (0.42) | ADRA2AADRA2BADRA2CTYRLMNA | |
| SCHEMBL2801986 | 0.81 | TYR (0.36) | ADRA2AADRA2BADRA2CTYRLMNA | |
| SCHEMBL11158917 | 0.80 | TYR (0.49) | ADRA2AADRA2BADRA2CTYRLMNA | |
| SCHEMBL7150196 | 0.78 | TAAR1 (0.54) | ADRA2AADRA2BADRA2CLMNAALOX15 | |
| SCHEMBL2987382 | 0.76 | ADRA2A (0.43) | ADRA2AADRA2BADRA2CTYRLMNA | |
| SCHEMBL2978320 | 0.75 | DPP4 (0.44) | ADRA2AADRA2BADRA2CLMNAALOX15 | |
| Monoethanolamine SCHEMBL11396682 | 0.73 | ADRA2A (0.38) | ADRA2AADRA2BADRA2CTYRLMNA | |
| SCHEMBL302560 | 0.72 | TYR (0.44) | ADRA2AADRA2BADRA2CTYRLMNA | |
| SCHEMBL31392616 | 0.72 | ADRA2A (0.47) | ADRA2AADRA2BADRA2CLMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5389286-A | Form films with good strength and mechanical integrity, can be blended with polyesters for fibers | UNIVERSITY OF MASSACHUSETTS AT AMHERST (US) | 1995-02-14 | — | — | US | disclosed |
| WO-1994009194-A1 | LIQUID CRYSTAL COPOLYMER CONTAINING ALKOXY-SUBSTITUTED PARA-PHENYLENE TEREPHTHALATE GROUPS | UNIVERSITY OF MASSACHUSETTS AT AMHERST (US) | 1994-04-28 | — | — | WO | disclosed |