Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 1/20 | 0.36 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.36 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.36 |
| ▸ | TYR | P14679 | 3/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.34 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | MIF | P14174 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.33 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9150470 | 0.93 | ADRA2A (0.38) | ADRA2AADRA2BADRA2CTYRNR1I2 | |
| SCHEMBL2801986 | 0.88 | TYR (0.36) | ADRA2AADRA2BADRA2CTYRNR1I2 | |
| SCHEMBL11158917 | 0.84 | TYR (0.49) | ADRA2AADRA2BADRA2CTYRALDH1A1 | |
| SCHEMBL9150253 | 0.79 | CYP3A4 (0.42) | ADRA2AADRA2BADRA2CTYRNR1I2 | |
| SCHEMBL1115157 | 0.78 | TSHR (0.42) | ADRA2AADRA2BADRA2CALDH1A1LMNA | |
| SCHEMBL7150196 | 0.75 | TAAR1 (0.54) | ADRA2AADRA2BADRA2CLMNAALOX15 | |
| SCHEMBL2987382 | 0.73 | ADRA2A (0.43) | ADRA2AADRA2BADRA2CTYRNR1I2 | |
| SCHEMBL28351212 | 0.73 | TAAR1 (0.52) | CNR1ALDH1A1LMNACYP2C9ALOX15 | |
| SCHEMBL2978320 | 0.72 | DPP4 (0.44) | ADRA2AADRA2BADRA2CLMNAALOX15 | |
| Monoethanolamine SCHEMBL11396682 | 0.70 | ADRA2A (0.38) | ADRA2AADRA2BADRA2CTYRNR1I2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010128038-A1 | HYDROQUINONE DERIVATIVES | AXOGLIA THERAPEUTICS S.A. (LU) | 2010-11-11 | — | — | WO | disclosed |