Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 4/20 | 0.46 |
| ▸ | RAB9A | P51151 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.43 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | HTR2B | P41595 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30283197 | 0.78 | SMN1; SMN2 (0.51) | SMN1; SMN2MAPK1NPC1RAB9AALDH1A1 | |
| SCHEMBL5451 | 0.78 | SMN1; SMN2 (0.51) | SMN1; SMN2MAPK1NPC1RAB9AALDH1A1 | |
| SCHEMBL28327211 | 0.77 | NPC1 (0.34) | SMN1; SMN2MAPK1NPC1RAB9AALDH1A1 | |
| SCHEMBL2776017 | 0.76 | ALDH1A1 (0.63) | SMN1; SMN2MAPK1NPC1RAB9AALDH1A1 | |
| Hydrochloric Acid SCHEMBL27764098 | 0.76 | NPC1 (0.50) | SMN1; SMN2MAPK1NPC1RAB9AALDH1A1 | |
| Guanidine SCHEMBL27910599 | 0.75 | GAA (0.40) | SMN1; SMN2NPC1RAB9AALDH1A1KDM4E | |
| SCHEMBL3426674 | 0.74 | ELANE (0.34) | SMN1; SMN2MAPK1NPC1RAB9AALDH1A1 | |
| SCHEMBL588390 | 0.73 | SMN1; SMN2 (0.46) | SMN1; SMN2MAPK1NPC1RAB9AALDH1A1 | |
| Hydrochloric Acid SCHEMBL28538972 | 0.72 | SMN1; SMN2 (0.44) | SMN1; SMN2MAPK1NPC1RAB9AALDH1A1 | |
| SCHEMBL19244400 | 0.72 | LMNA (0.56) | SMN1; SMN2MAPK1NPC1RAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104829756-A | Solid catalyst component for olefin polymerization, and preparation method and application thereof | CHINESE ACAD INST CHEMISTRY | 2015-08-12 | — | — | CN | disclosed |