Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 1/20 | 0.34 |
| ▸ | AR | P10275 | 5/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | THRB | P10828 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | THRA | P10827 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | NAMPT | P43490 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 3/20 | 0.31 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8145380 | 0.82 | SMN1; SMN2 (0.41) | ARALDH1A1THRBSMN1; SMN2KDM4E | |
| SCHEMBL9707104 | 0.79 | THRB (0.47) | ELANEALDH1A1THRBKDM4ETHRA | |
| SCHEMBL1245242 | 0.76 | TSHR (0.42) | ARALDH1A1THRBSMN1; SMN2KDM4E | |
| SCHEMBL3423786 | 0.74 | THRB (0.33) | ARALDH1A1THRBSMN1; SMN2MAPK1 | |
| SCHEMBL28020073 | 0.74 | SMN1; SMN2 (0.47) | ARALDH1A1THRBSMN1; SMN2KDM4E | |
| SCHEMBL2221010 | 0.73 | ELANE (0.49) | ELANEALDH1A1KDM4EMAPK1HPGD | |
| SCHEMBL4070955 | 0.73 | KMT2A (0.36) | ALDH1A1THRBSMN1; SMN2KDM4ETP53 | |
| SCHEMBL588390 | 0.72 | SMN1; SMN2 (0.46) | ALDH1A1THRBSMN1; SMN2KDM4ETP53 | |
| SCHEMBL16958507 | 0.72 | ELANE (0.37) | ELANE | |
| SCHEMBL28065492 | 0.72 | THRB (0.40) | ALDH1A1THRBSMN1; SMN2KDM4ETP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7700306-B2 | characterising a polypeptide by matrix assisted laser desorption ionization (MALDI) mass spectrometry; improving sensitivity, and can increase the number of peptides that are detected from a protein | ELECTROPHORETICS LIMITED (GB) | 2010-04-20 | — | — | US | disclosed |
| US-20060040334-A1 | Method for characterising analytes | XZILLION GMBH & CO. KG (DE) | 2006-02-23 | — | — | US | disclosed |
| EP-1490693-A1 | METHOD FOR CHARACTERISING ANALYTES | Xzillion GmbH & CO.KG (DE) | 2004-12-29 | — | — | EP | disclosed |
| WO-2003087839-A1 | METHOD FOR CHARACTERISING ANALYTES | XZILLION GMBH & CO. KG (DE) | 2003-10-23 | — | — | WO | disclosed |