Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 2/20 | 0.53 |
| ▸ | DRD2 | P14416 | 2/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | ABCB1 | P08183 | 6/20 | 0.48 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.48 |
| ▸ | TRPV6 | Q9H1D0 | 1/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.45 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | MGLL | Q99685 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15583063 | 0.88 | HTR1A (0.51) | HTR1ADRD2L3MBTL1LMNAABCB1 | |
| SCHEMBL16797594 | 0.85 | HTR1A (0.53) | HTR1ADRD2L3MBTL1LMNAABCB1 | |
| SCHEMBL18894534 | 0.85 | HTR1A (0.53) | HTR1ADRD2L3MBTL1LMNAABCB1 | |
| SCHEMBL23881745 | 0.84 | HTR1A (0.73) | HTR1ADRD2L3MBTL1LMNAABCB1 | |
| SCHEMBL27402118 | 0.83 | CCR5 (0.60) | HTR1ADRD2LMNAALDH1A1PTGER1 | |
| SCHEMBL6370737 | 0.82 | HTR1A (0.49) | HTR1ADRD2ABCB1ABCG2FFAR1 | |
| SCHEMBL7450663 | 0.81 | HTR1A (0.51) | HTR1ADRD2L3MBTL1LMNAABCB1 | |
| SCHEMBL6216285 | 0.81 | ELANE (0.53) | HTR1ADRD2L3MBTL1LMNAABCB1 | |
| SCHEMBL6216693 | 0.81 | HTR1A (0.51) | HTR1ADRD2L3MBTL1LMNAABCB1 | |
| SCHEMBL20006769 | 0.81 | HTR1A (0.49) | HTR1ADRD2L3MBTL1LMNAABCB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104650022-A | Synthesis method and intermediate compound of nebivolol | ZHEJIANG AUSUN PHARMACEUTICAL CO LTD | 2015-05-27 | — | — | CN | claimed |
| CN-104650022-A | Synthesis method and intermediate compound of nebivolol | ZHEJIANG AUSUN PHARMACEUTICAL CO LTD | 2015-05-27 | — | — | CN | disclosed |