Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 2/20 | 0.51 |
| ▸ | DRD2 | P14416 | 2/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | ABCB1 | P08183 | 3/20 | 0.47 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | TRPV6 | Q9H1D0 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.44 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.44 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.43 |
| ▸ | MGLL | Q99685 | 1/20 | 0.43 |
| ▸ | LIPE | Q05469 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2394736 | 0.87 | L3MBTL1 (0.48) | HTR1ADRD2L3MBTL1LMNAALDH1A1 | |
| SCHEMBL15583063 | 0.84 | HTR1A (0.51) | HTR1ADRD2L3MBTL1LMNAABCB1 | |
| SCHEMBL6216693 | 0.84 | HTR1A (0.51) | HTR1ADRD2L3MBTL1LMNAABCB1 | |
| SCHEMBL6216285 | 0.84 | ELANE (0.53) | HTR1ADRD2L3MBTL1LMNAABCB1 | |
| SCHEMBL547985 | 0.83 | HTR1A (0.67) | HTR1ADRD2L3MBTL1LMNAABCB1 | |
| SCHEMBL4720836 | 0.82 | PTGER1 (0.56) | — | |
| SCHEMBL8991584 | 0.82 | ALOX5 (0.54) | HTR1ADRD2L3MBTL1LMNAABCB1 | |
| SCHEMBL32670477 | 0.81 | ALDH1A1 (0.62) | HTR1ADRD2LMNAABCB1ALDH1A1 | |
| SCHEMBL16797594 | 0.81 | HTR1A (0.53) | HTR1ADRD2L3MBTL1LMNAABCB1 | |
| SCHEMBL28020148 | 0.81 | HTR1A (0.53) | HTR1ADRD2L3MBTL1LMNAABCB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1175385-A1 | D-MANNITOL DERIVATIVES AS HIV ASPARTYL PROTEASE INHIBITORS | Pharmacor Inc. (CA) | 2002-01-30 | — | — | EP | disclosed |
| WO-2000066524-A1 | D-MANNITOL DERIVATIVES AS HIV ASPARTYL PROTEASE INHIBITORS | PHARMACOR INC. (CA) | 2000-11-09 | — | — | WO | disclosed |