Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 2/20 | 0.49 |
| ▸ | DRD2 | P14416 | 2/20 | 0.49 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.45 |
| ▸ | APP | P05067 | 4/20 | 0.44 |
| ▸ | CCR5 | P51681 | 1/20 | 0.43 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.42 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.42 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.42 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.42 |
| ▸ | ABCB1 | P08183 | 3/20 | 0.42 |
| ▸ | USP28 | Q96RU2 | 1/20 | 0.42 |
| ▸ | USP25 | Q9UHP3 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1021663 | 0.88 | CCR5 (0.48) | HTR1ADRD2FFAR1APPCCR5 | |
| SCHEMBL27402118 | 0.83 | CCR5 (0.60) | HTR1ADRD2CCR5PTGER1USP28 | |
| SCHEMBL28020148 | 0.82 | HTR1A (0.53) | HTR1ADRD2FFAR1PTGER1ABCB1 | |
| SCHEMBL6213896 | 0.81 | CCR5 (0.49) | HTR1ADRD2FFAR1APPCCR5 | |
| SCHEMBL1023923 | 0.81 | ELANE (0.53) | HTR1ADRD2FFAR1APPCCR5 | |
| SCHEMBL23881745 | 0.80 | HTR1A (0.73) | HTR1ADRD2PTGER1PTGER4PTGER3 | |
| SCHEMBL31375355 | 0.79 | APP (0.56) | HTR1ADRD2FFAR1APPRAB9A | |
| SCHEMBL11647126 | 0.79 | APP (0.56) | HTR1ADRD2FFAR1APPRAB9A | |
| SCHEMBL17488405 | 0.78 | RAB9A (0.56) | FFAR1APPRAB9A | |
| SCHEMBL28843836 | 0.77 | FFAR1 (0.59) | HTR1ADRD2FFAR1APP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101090909-A | Antibacterial amide macrocycles IV | AICURIS GMBH & CO KG (DE) | 2007-12-19 | — | — | CN | disclosed |
| CN-1326870-C | Antibacterial amide macrocycles | BAYER HEALTHCARE AG (DE) | 2007-07-18 | — | — | CN | disclosed |
| US-20050256037-A1 | Antibacterial amide macrocyles | BAYER HEALTHCARE AG (DE) | 2005-11-17 | — | — | US | disclosed |
| CN-1675236-A | Antibacterial amide macrocycles | BAYER HEALTHCARE AG (DE) | 2005-09-28 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050256037-A1 | Antibacterial amide macrocyles | AADAC, PAM, NOD2 | HTR1A 4576/4885DRD2 3865/4885FFAR1 3481/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.