Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE2A | O00408 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | AHR | P35869 | 1/20 | 0.39 |
| ▸ | JAK2 | O60674 | 1/20 | 0.39 |
| ▸ | JAK1 | P23458 | 1/20 | 0.39 |
| ▸ | TYK2 | P29597 | 1/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.39 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3822269 | 0.81 | PDE2A (0.50) | PDE2AALDH1A1TSHRMEN1KMT2A | |
| SCHEMBL980201 | 0.80 | TSHR (0.61) | PDE2AALDH1A1TSHRMEN1KMT2A | |
| SCHEMBL29402881 | 0.80 | TSHR (0.61) | PDE2AALDH1A1TSHRMEN1KMT2A | |
| SCHEMBL19785385 | 0.78 | PDE2A (0.47) | PDE2AALDH1A1TSHRMEN1KMT2A | |
| Ammonia Solution, Strong SCHEMBL28020319 | 0.78 | TSHR (0.58) | PDE2AALDH1A1TSHRMEN1KMT2A | |
| SCHEMBL30326145 | 0.76 | PDE2A (0.46) | PDE2AALDH1A1TSHRMEN1KMT2A | |
| SCHEMBL30418237 | 0.76 | CES2 (0.50) | PDE2AALDH1A1 | |
| SCHEMBL5756914 | 0.76 | PDE2A (0.46) | PDE2AALDH1A1TSHRMEN1KMT2A | |
| SCHEMBL171040 | 0.76 | PDE2A (0.50) | PDE2AALDH1A1TSHRMEN1KMT2A | |
| SCHEMBL1040760 | 0.76 | CES2 (0.50) | PDE2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE49948-E1 | Aryl ethers and uses thereof | PELOTON THERAPEUTICS, INC. (US) | 2024-04-30 | — | — | US | disclosed |
| CN-110372550-B | Aryl ethers and their use | 佩洛通治疗公司 | 2021-08-24 | — | — | CN | disclosed |
| EP-3417851-B1 | ARYL ETHERS AND USES THEREOF | PELOTON THERAPEUTICS INC (US) | 2020-07-22 | — | — | EP | disclosed |
| US-20200190031-A1 | ARYL ETHERS AND USES THEREOF | PELOTON THERAPEUTICS, INC. (US) | 2020-06-18 | — | — | US | disclosed |
| US-10597366-B2 | Aryl ethers and uses thereof | PELOTON THERAPEUTICS, INC. (US) | 2020-03-24 | — | — | US | disclosed |
| EP-3417852-B1 | ARYL ETHERS AND USES THEREOF | PELOTON THERAPEUTICS INC (US) | 2020-02-19 | — | — | EP | disclosed |
| EP-3043784-B9 | ARYL ETHERS AND USES THEREOF | PELOTON THERAPEUTICS INC (US) | 2019-11-20 | — | — | EP | disclosed |
| CN-110372550-A | Aryl ether and application thereof | 佩洛通治疗公司 | 2019-10-25 | — | — | CN | disclosed |
| CN-105530923-B | Aryl ethers and their use | 佩洛通治疗公司 | 2019-07-23 | — | — | CN | disclosed |
| EP-3043784-B1 | ARYL ETHERS AND USES THEREOF | PELOTON THERAPEUTICS INC (US) | 2019-05-15 | — | — | EP | disclosed |
| CN-1209019-C | Herbicides containing substituted pyrazole derivatives as active ingredient | SDS BIOTECH CORP (JP) | 2005-07-06 | — | — | CN | disclosed |
| US-6809065-B2 | ON ALGAE OR WEEDS; CROP SELECTIVITY | SDS BIOTECH K.K. (JP) | 2004-10-26 | — | — | US | disclosed |
| EP-1407667-A1 | HERBICIDE CONTAINING SUBSTITUTED PYRAZOLE DERIVATIVE AS ACTIVE INGREDIENT | SDS Biotech K.K. (JP) | 2004-04-14 | — | — | EP | disclosed |
| US-20040033898-A1 | Herbicide containing substituted pyrazole derivative as active ingredient | SDS BIOTECH K.K. (JP) | 2004-02-19 | — | — | US | disclosed |
| CN-1464772-A | Herbicide containing substituted pyrazole derivative as active ingredient | SDS BIOTECH CORP (JP) | 2003-12-31 | — | — | CN | disclosed |
| EP-0945437-A1 | Pyrazolyl acrylic acid- and pyrazolyl oximino-acetic acid derivatives, their preparation and their use as fungicides | SDS Biotech K.K. (JP) | 1999-09-29 | — | — | EP | disclosed |
| EP-0458684-B1 | Reagent and process for the perfluoroalkylation of nucleophilic substrates by sodium perfluoroalkanesulfinates in an oxidising medium | RHODIA CHIMIE SA (FR) | 1998-11-11 | — | — | EP | disclosed |
| EP-0458684-A1 | Reagent and process for the perfluoroalkylation of nucleophilic substrates by sodium perfluoroalkanesulfinates in an oxidising medium | RHONE-POULENC CHIMIE (FR) | 1991-11-27 | — | — | EP | disclosed |
| US-4154967-A | OXIDATION OF ISOPROPYLAROMATIC HYDROCARBON IN THE PRESENCE OF AROMATIC MERCAPTAN | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1979-05-15 | — | — | US | disclosed |
| US-3966769-A | Sulfonyl compounds | CASSELLA FARBWERKE MAINKUR AKTIENGESELLSCHAFT (DT) | 1976-06-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200190031-A1 | ARYL ETHERS AND USES THEREOF | HIF1AN, EGLN2, VHL | PDE2A 210/4885ALDH1A1 497/4885TSHR 1110/4885 |
| US-10597366-B2 | Aryl ethers and uses thereof | HIF1AN, EGLN2, VHL | PDE2A 210/4885ALDH1A1 497/4885TSHR 1110/4885 |
| US-20040033898-A1 | Herbicide containing substituted pyrazole derivative as active ingredient | DDT, SULT2A1, CYP2E1 | PDE2A 2905/4885ALDH1A1 365/4885TSHR 2846/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.