SCHEMBL28020525

SCHEMBL28020525

COc1oc2c(CO)cc(O)c(OC)c2c(=O)c1-c1ccccc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.45
CYP3A4 P08684 3/20 0.45
PKM P14618 2/20 0.45
GABRP O00591 1/20 0.45
GABRD O14764 1/20 0.45
KDM1A O60341 1/20 0.45
CCNT1 O60563 1/20 0.45
GABRA1 P14867 1/20 0.45
GABRB1 P18505 1/20 0.45
GABRG2 P18507 1/20 0.45
CCNA2 P20248 1/20 0.45
CCNC P24863 1/20 0.45
CDK2 P24941 1/20 0.45
GABRB3 P28472 1/20 0.45
GABRA5 P31644 1/20 0.45
GABRA3 P34903 1/20 0.45
PTGS2 P35354 1/20 0.45
GABRA2 P47869 1/20 0.45
GABRB2 P47870 1/20 0.45
GABRA4 P48169 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31517127 0.78 ALDH1A1 (0.53) ALDH1A1CYP3A4PKMGABRPGABRD
SCHEMBL1248240 0.78 ALDH1A1 (0.60) ALDH1A1CYP3A4PKMGABRPGABRD
SCHEMBL27770682 0.78 ALDH1A1 (0.53) ALDH1A1CYP3A4PKMGABRPGABRD
SCHEMBL1249227 0.74 SI (0.53) ALDH1A1CYP3A4PKMGABRPGABRD
SCHEMBL30527883 0.71 MEN1 (0.67) ALDH1A1CYP3A4GABRPGABRDGABRA1
SCHEMBL27728663 0.71 ABCB1 (0.57) ALDH1A1CYP3A4PTGS2ABCB1SLCO2B1
SCHEMBL27454803 0.69 CREB1 (0.55) ALDH1A1CYP3A4PKMGABRPGABRD
SCHEMBL4287360 0.69 ALDH1A1 (0.55) ALDH1A1CYP3A4ABCB1MAPTMEN1
SCHEMBL6724444 0.68 CYP3A4 (0.51) ALDH1A1CYP3A4ABCB1KDM4EMAPT
SCHEMBL11244826 0.68 MEN1 (0.52) ALDH1A1CYP3A4ABCB1ACHEKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104761526-B A kind of isoflavonoid with antiviral activity and its preparation method and application 云南中烟工业有限责任公司 2017-03-08 CN disclosed
CN-104761526-A Isoflavone compound with anti-virus activity as well as preparation method and application thereof CHINA TOBACCO YUNNAN IND CO LTD 2015-07-08 CN disclosed