Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | MAOA | P21397 | 1/20 | 0.54 |
| ▸ | ABCB1 | P08183 | 3/20 | 0.50 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.50 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 3/20 | 0.48 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.45 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27728663 | 0.89 | ABCB1 (0.57) | ALDH1A1CYP3A4ABCB1ABCG2ADORA3 | |
| SCHEMBL737207 | 0.87 | ADORA3 (0.58) | ALDH1A1CYP3A4MAOAABCB1ABCG2 | |
| SCHEMBL6724444 | 0.86 | CYP3A4 (0.51) | ALDH1A1CYP3A4MAOAABCB1ABCG2 | |
| SCHEMBL10619800 | 0.86 | MEN1 (0.63) | ALDH1A1CYP3A4MAOAABCB1ABCG2 | |
| SCHEMBL1249227 | 0.82 | SI (0.53) | ALDH1A1CYP3A4MAOAABCB1ABCG2 | |
| SCHEMBL774317 | 0.81 | ADORA3 (0.72) | ALDH1A1CYP3A4MAOAABCB1ABCG2 | |
| SCHEMBL896579 | 0.81 | MAOA (0.57) | ALDH1A1CYP3A4MAOAABCG2ADORA3 | |
| SCHEMBL11244826 | 0.81 | MEN1 (0.52) | ALDH1A1CYP3A4MAOAABCB1ABCG2 | |
| SCHEMBL28066116 | 0.78 | MKNK2 (0.63) | ALDH1A1CYP3A4MAOAABCB1ABCG2 | |
| SCHEMBL27770682 | 0.78 | ALDH1A1 (0.53) | ALDH1A1CYP3A4ABCB1ABCG2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111574490-A | Synthesis method of polyhydroxy isoflavone | 中国人民解放军联勤保障部队第九〇四医院 | 2020-08-25 | — | — | CN | claimed |
| CN-111560000-A | Synthesis method of polyhydroxy isoflavone | 中国人民解放军联勤保障部队第九〇四医院 | 2020-08-21 | — | — | CN | claimed |
| CN-102351827-A | Isoflavone compound in tobacco rhizome and preparation method and application thereof | YUNNAN TOBACCO SCI RES INST | 2012-02-15 | — | — | CN | claimed |
| CN-101343253-B | 2-amido-4, 5-diaryl miazines compound, preparation and pharmaceutical use thereof | UNIV SHANXI NORMAL | 2011-03-16 | — | — | CN | claimed |
| CN-101456845-B | 4,5-diaryl-2-sulfhydryl miazines compounds and synthetic method thereof and pharmaceutical use | UNIV SHAANXI NORMAL | 2010-11-03 | — | — | CN | claimed |
| CN-101797265-A | Application of belamcanda chinensis total isoflavone or isoflavone compounds in preparing medicaments and food for preventing and treating women's disease | UNIV PLA 2ND MILITARY MEDICAL | 2010-08-11 | — | — | CN | claimed |
| CN-101456845-A | 4,5-diaryl-2-sulfhydryl miazines compounds and synthetic method thereof and pharmaceutical use | UNIV SHAANXI NORMAL (CN) | 2009-06-17 | — | — | CN | claimed |
| CN-101343253-A | 2-amido-4, 5-diaryl miazines compound, preparation and pharmaceutical use thereof | UNIV SHAANXI NORMAL (CN) | 2009-01-14 | — | — | CN | claimed |
| CN-101020662-A | Compound 3,4-diaryl pyrazole and its prepn and medicinal use | UNIV SHAANXI NORMAL (CN) | 2007-08-22 | — | — | CN | claimed |
| CN-1986556-A | Blackberry lily isoflavone compound and its application in medical field | UNIV PLA 2ND MILITARY MEDICAL (CN) | 2007-06-27 | — | — | CN | claimed |
| CN-107596247-B | Mongolian medicine for treating lung disease and its preparing process | 内蒙古民族大学附属医院 | 2020-12-22 | — | — | CN | disclosed |
| CN-111574490-A | Synthesis method of polyhydroxy isoflavone | 中国人民解放军联勤保障部队第九〇四医院 | 2020-08-25 | — | — | CN | disclosed |
| CN-111560000-A | Synthesis method of polyhydroxy isoflavone | 中国人民解放军联勤保障部队第九〇四医院 | 2020-08-21 | — | — | CN | disclosed |
| US-9757378-B2 | Methods to modulate acute myeloid leukemia stem/progenitor cell expansion and/or differentiation | UNIVERSITE DE MONTREAL (CA) | 2017-09-12 | — | — | US | disclosed |
| CN-104592189-B | A kind of isoflavonoid, its preparation method and application | 中国科学院成都生物研究所 | 2017-01-04 | — | — | CN | disclosed |
| CN-101343253-A | 2-amido-4, 5-diaryl miazines compound, preparation and pharmaceutical use thereof | UNIV SHAANXI NORMAL (CN) | 2009-01-14 | — | — | CN | disclosed |
| CN-101020662-A | Compound 3,4-diaryl pyrazole and its prepn and medicinal use | UNIV SHAANXI NORMAL (CN) | 2007-08-22 | — | — | CN | disclosed |
| CN-1986556-A | Blackberry lily isoflavone compound and its application in medical field | UNIV PLA 2ND MILITARY MEDICAL (CN) | 2007-06-27 | — | — | CN | disclosed |
| US-6589980-B2 | A compound which is 2,6-dihydroxy-8-methoxy-10,11-dioxa-benzo(b)fluoren-5-one or a pharmaceutically acceptable salt for treating or inhibiting osteoporosis or inhibiting bone demineralization in a mammal in need thereof | WYETH | 2003-07-08 | — | — | US | disclosed |
| US-20030087955-A1 | Substituted 10,11-benzo[b]fluoren-10-ones as estrogenic agents | WYETH | 2003-05-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030087955-A1 | Substituted 10,11-benzo[b]fluoren-10-ones as estrogenic agents | ESR1, GPER1, ESR2 | ALDH1A1 1276/4885CYP3A4 273/4885MAOA 1794/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.