Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.62 |
| ▸ | POLB | P06746 | 4/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.62 |
| ▸ | HPGD | P15428 | 1/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.60 |
| ▸ | HTT | P42858 | 3/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.60 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.54 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.54 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.54 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.54 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28820179 | 0.90 | MEN1 (0.52) | MEN1KMT2APOLBALDH1A1HPGD | |
| SCHEMBL28020698 | 0.86 | ALDH1A1 (0.65) | MEN1KMT2APOLBALDH1A1HPGD | |
| SCHEMBL28820180 | 0.85 | MEN1 (0.60) | MEN1KMT2APOLBALDH1A1HPGD | |
| SCHEMBL28020308 | 0.84 | PTGDR2 (0.50) | MEN1KMT2APOLBALDH1A1HPGD | |
| SCHEMBL28020357 | 0.79 | BCHE (0.68) | MEN1KMT2APOLBALDH1A1HPGD | |
| SCHEMBL25179157 | 0.78 | GAA (0.71) | MEN1KMT2APOLBALDH1A1HTT | |
| SCHEMBL28020363 | 0.78 | ALDH1A1 (0.58) | MEN1KMT2AALDH1A1HPGDKDM4E | |
| SCHEMBL15757807 | 0.78 | KMT2A (0.78) | MEN1KMT2APOLBALDH1A1KDM4E | |
| SCHEMBL19511969 | 0.77 | ALDH1A1 (0.60) | MEN1KMT2AALDH1A1HPGDKDM4E | |
| SCHEMBL6782525 | 0.76 | ALDH1A1 (0.55) | MEN1KMT2APOLBALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102775381-B | Substituted hydrazide compound, and its preparation method, medicinal compositions and application | SHANGHAI INST MATERIA MEDICA | 2015-05-20 | — | — | CN | disclosed |