Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.52 |
| ▸ | SMO | Q99835 | 2/20 | 0.52 |
| ▸ | HTT | P42858 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 4/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | MAOB | P27338 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28020740 | 0.90 | MEN1 (0.62) | MEN1KMT2AHTTLMNAMAPT | |
| SCHEMBL28020363 | 0.87 | ALDH1A1 (0.58) | MEN1KMT2AHTTLMNAMAPT | |
| SCHEMBL28020305 | 0.85 | EPHX2 (0.58) | KMT2AHTTLMNAMAPTPOLB | |
| SCHEMBL28820180 | 0.81 | MEN1 (0.60) | MEN1KMT2AHTTLMNAMAPT | |
| SCHEMBL28020308 | 0.80 | PTGDR2 (0.50) | MEN1KMT2AHTTLMNAMAPT | |
| SCHEMBL28020698 | 0.77 | ALDH1A1 (0.65) | MEN1KMT2AHTTLMNAMAPT | |
| SCHEMBL25179157 | 0.74 | GAA (0.71) | MEN1KMT2AHTTLMNAMAPT | |
| SCHEMBL19511969 | 0.73 | ALDH1A1 (0.60) | MEN1KMT2ALMNAMAPTALDH1A1 | |
| SCHEMBL6782525 | 0.72 | ALDH1A1 (0.55) | MEN1KMT2AHTTLMNAMAPT | |
| SCHEMBL15757807 | 0.71 | KMT2A (0.78) | MEN1KMT2AHTTLMNAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102775381-B | Substituted hydrazide compound, and its preparation method, medicinal compositions and application | SHANGHAI INST MATERIA MEDICA | 2015-05-20 | — | — | CN | disclosed |