Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.60 |
| ▸ | LMNA | P02545 | 2/20 | 0.60 |
| ▸ | MAPT | P10636 | 2/20 | 0.60 |
| ▸ | HTT | P42858 | 2/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.60 |
| ▸ | POLB | P06746 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | MAOB | P27338 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28020740 | 0.85 | MEN1 (0.62) | MEN1KMT2ALMNAMAPTHTT | |
| SCHEMBL28820179 | 0.81 | MEN1 (0.52) | MEN1KMT2ALMNAMAPTHTT | |
| SCHEMBL25179157 | 0.81 | GAA (0.71) | MEN1KMT2ALMNAMAPTHTT | |
| SCHEMBL1203812 | 0.80 | LOXL2 (0.54) | MEN1KMT2ALMNAMAPTHTT | |
| SCHEMBL12231041 | 0.79 | BCAT2 (0.58) | MEN1KMT2ALMNAMAPTHTT | |
| SCHEMBL28020308 | 0.78 | PTGDR2 (0.50) | MEN1KMT2ALMNAMAPTHTT | |
| SCHEMBL6782525 | 0.76 | ALDH1A1 (0.55) | MEN1KMT2ALMNAMAPTHTT | |
| SCHEMBL15757998 | 0.75 | MEN1 (0.61) | MEN1KMT2ALMNAMAPTHTT | |
| SCHEMBL29994706 | 0.75 | HPGD (0.62) | MEN1KMT2ALMNAMAPTHTT | |
| SCHEMBL1202191 | 0.75 | HPGD (0.62) | MEN1KMT2ALMNAMAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102775381-B | Substituted hydrazide compound, and its preparation method, medicinal compositions and application | SHANGHAI INST MATERIA MEDICA | 2015-05-20 | — | — | CN | disclosed |