Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 5/20 | 0.49 |
| ▸ | RPA1 | P27694 | 1/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.47 |
| ▸ | FAAH | O00519 | 4/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | MGLL | Q99685 | 1/20 | 0.41 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6494672 | 0.86 | RPA1 (0.54) | PTGS2RPA1PTGS1FAAHALDH1A1 | |
| SCHEMBL1984665 | 0.83 | RPA1 (0.68) | PTGS2RPA1PTGS1ALDH1A1KDM4E | |
| SCHEMBL30279510 | 0.83 | FAAH (0.46) | PTGS2FAAHTP53ALDH1A1POLB | |
| SCHEMBL1995003 | 0.82 | RPA1 (0.50) | PTGS2RPA1PTGS1FAAHALDH1A1 | |
| SCHEMBL1999172 | 0.82 | PTGS1 (0.56) | PTGS2RPA1PTGS1FAAHALDH1A1 | |
| SCHEMBL13389277 | 0.80 | ALDH1A1 (0.60) | FAAHTP53ALDH1A1POLBKDM4E | |
| SCHEMBL18622977 | 0.74 | KDM4E (0.72) | PTGS2RPA1PTGS1TP53ALDH1A1 | |
| SCHEMBL9054421 | 0.74 | CA9 (0.65) | PTGS2RPA1FAAHTP53CHRNA7 | |
| SCHEMBL3831473 | 0.73 | ALDH1A1 (0.46) | FAAHTP53ALDH1A1POLBKDM4E | |
| SCHEMBL9465353 | 0.72 | PTGS2 (0.66) | PTGS2RPA1PTGS1ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104744461-A | Lactam-containing compounds and derivatives thereof as factor Xa inhibitors | BRISTOL MYERS SQUIBB CO | 2015-07-01 | — | — | CN | disclosed |