Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 4/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | GAPDH | P04406 | 1/20 | 0.39 |
| ▸ | F2RL1 | P55085 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 3/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | BCHE | P06276 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19303207 | 0.70 | MAPT (0.44) | ALDH1A1PKMTP53LMNANPC1 | |
| SCHEMBL18508392 | 0.66 | ALDH1A1 (0.47) | ALDH1A1KMT2APOLBTDP1KDM4E | |
| SCHEMBL300491 | 0.64 | ALOX15 (0.41) | ALDH1A1KMT2ATDP1F2RL1KDM4E | |
| SCHEMBL311710 | 0.62 | BCHE (0.42) | ALDH1A1KMT2AF2RL1ALOX15TP53 | |
| SCHEMBL21325363 | 0.61 | BCHE (0.34) | KMT2APOLBKDM4ETP53MEN1 | |
| SCHEMBL628830 | 0.60 | MEN1 (0.34) | ALDH1A1KMT2ATDP1KDM4EMEN1 | |
| SCHEMBL5394656 | 0.59 | CYP1A2 (0.37) | ALDH1A1KMT2APOLBTDP1KDM4E | |
| SCHEMBL10274656 | 0.59 | CYP1A2 (0.37) | ALDH1A1KMT2APOLBTDP1KDM4E | |
| SCHEMBL943173 | 0.59 | CYP1A2 (0.37) | ALDH1A1KMT2APOLBTDP1KDM4E | |
| SCHEMBL31759376 | 0.59 | CYP1A2 (0.37) | ALDH1A1KMT2APOLBTDP1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104768554-A | Triazolo compounds | HOFFMANN LA ROCHE | 2015-07-08 | — | — | CN | disclosed |