Sugi Predict

Sugi Predict / Compounds / SCHEMBL311710

SCHEMBL311710

SCHEMBL311710

c1c[nH]c(N2CCCCC2)n1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ BCHE P06276 1/20 0.42
▸ ACHE P22303 1/20 0.42
▸ JAK3 P52333 2/20 0.40
▸ ALOX15 P16050 2/20 0.39
▸ F2RL1 P55085 3/20 0.38
▸ HIPK2 Q9H2X6 1/20 0.38
▸ SMN1; SMN2 Q16637 2/20 0.38
▸ TP53 P04637 2/20 0.38
▸ NPC1 O15118 1/20 0.38
▸ HPGD P15428 1/20 0.38
▸ TSHR P16473 1/20 0.38
▸ NFKB1 P19838 1/20 0.38
▸ RAB9A P51151 1/20 0.38
▸ GFER P55789 1/20 0.38
▸ NFKB2 Q00653 1/20 0.38
▸ RELA Q04206 1/20 0.38
▸ HTT P42858 3/20 0.37
▸ LMNA P02545 1/20 0.37
▸ AKT2 P31751 1/20 0.37
▸ MAP3K5 Q99683 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL29375122 0.98 BCHE (0.41) BCHEACHEJAK3ALOX15F2RL1
SCHEMBL300491 0.98 ALOX15 (0.41) BCHEACHEJAK3ALOX15F2RL1
Hydrochloric Acid SCHEMBL9200760 0.91 ALOX15 (0.39) BCHEACHEJAK3ALOX15F2RL1
Imidazole SCHEMBL8028921 0.86 ALDH1A1 (0.42) BCHEACHEJAK3ALOX15F2RL1
SCHEMBL3096843 0.81 KDM4E (0.48) ALOX15HRH3ALDH1A1
SCHEMBL4456263 0.79 KDM4E (0.47) HRH3ALDH1A1
SCHEMBL6904489 0.79 TP53 (0.45) JAK3ALOX15HIPK2SMN1; SMN2TP53
SCHEMBL6840293 0.79 NPC1 (0.41) NPC1RAB9AHTTMEN1KMT2A
SCHEMBL21047581 0.78 HIPK2 (0.42) ALOX15HIPK2SMN1; SMN2LMNAALDH1A1
SCHEMBL6281359 0.76 AKT2 (0.49) ALOX15HIPK2TSHRNFKB1AKT2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 168 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120046288-A1 Hydrazonamide Compounds That Modulate Hsp90 Activity Synta Pharmacueticals Corp. 2012-02-23 — — US claimed
US-7816529-B2 Pyrimidines useful as modulators of voltage-gated ion channels VERTEX PHARMACEUTICALS INCORPORATED (US) 2010-10-19 — — US claimed
US-6936711-B2 Process for preparation of penam derivatives from cepham derivatives ORCHID CHEMICALS AND PHARMACEUTICALS LIMITED (US) 2005-08-30 — — US claimed
US-6639062-B2 Oligonucleotides which elicit ribonuclease for cleavage in complementary nucleic acid strand, having increased binding affinity/nuclease resistance; for medical diagnosis, gene therapy ISIS PHARMACEUTICALS, INC. 2003-10-28 — — US claimed
US-5071855-A Antihistamines, antiallergens DOMPE FARMACEUTICI SPA (IT) 1991-12-10 — — US claimed
US-4980348-A HETEROANELLATED PHENYLGLYCINE-BETA-LACTAM ANTIBIOTICS BAYER AKTIENGESELLSCHAFT (DE) 1990-12-25 — — US claimed
EP-0397614-A2 Pharmacologically active piperdinylimidazopyridines DOMPE' FARMACEUTICI S.p.A. (IT) 1990-11-14 — — EP claimed
CN-117946111-A Aryl heterocycle Kv1.3 inhibitor and preparation method and application thereof 上海深势唯思科技有限责任公司 2024-04-30 — — CN disclosed
CN-113631548-B Serotonin 5-HT2B inhibiting compounds 硕腾服务有限责任公司 2023-06-06 — — CN disclosed
CN-113631548-A Serotonin 5-HT2B inhibiting compounds 硕腾服务有限责任公司 2021-11-09 — — CN disclosed
CN-109694367-B Method for preparing bilastine 湖北省医药工业研究院有限公司 2021-06-11 — — CN disclosed
US-10889553-B2 Asymmetric triazole benzamide derivatives and the compositions and methods of treatment regarding the same NYSNOBIO IRELAND DAC (IE) 2021-01-12 — — US disclosed
US-20200362083-A1 NOVEL COPOLYMER AND USE THEREOF AS A FUEL ADDITIVE TOTAL MARKETING SERVICES (FR) 2020-11-19 — — US disclosed
CN-1041363-A PROCESS FOR PREPARING IMIDAZOLE ANTIARRHYTHMICS MERRELL DOW PHARMA (US) 1990-04-18 — — CN disclosed
CN-1041363-A PROCESS FOR PREPARING IMIDAZOLE ANTIARRHYTHMICS MERRELL DOW PHARMA (US) 1990-04-18 — — CN disclosed
EP-0360275-A2 Imidazole antiarrhythmics MERRELL DOW PHARMACEUTICALS INC. (US) 1990-03-28 — — EP disclosed
EP-0360275-A2 Imidazole antiarrhythmics MERRELL DOW PHARMACEUTICALS INC. (US) 1990-03-28 — — EP disclosed
US-4868194-A Imidazole antiarrhythmics MERRELL DOW PHARMACEUTICALS INC. (US) 1989-09-19 — — US disclosed
US-4868194-A Imidazole antiarrhythmics MERRELL DOW PHARMACEUTICALS INC. (US) 1989-09-19 — — US disclosed
US-3989673-A Low temperature curing resin system HUGHES AIRCRAFT COMPANY (US) 1976-11-02 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120046288-A1 Hydrazonamide Compounds That Modulate Hsp90 Activity HSP90AB1, HSP90AA1, HSP90AB2P BCHE 4827/4885ACHE 4872/4885JAK3 2426/4885
US-10889553-B2 Asymmetric triazole benzamide derivatives and the compositions and methods of treatment regarding the same ATG7, PINK1, ADRM1 BCHE 924/4885ACHE 1538/4885JAK3 397/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.