Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FASN | P49327 | 7/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | PLAT | P00750 | 1/20 | 0.37 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.36 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HTR7 | P34969 | 1/20 | 0.35 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.35 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2800033 | 0.96 | ALDH1A1 (0.43) | FASNALDH1A1PLATEGLN1SMN1; SMN2 | |
| SCHEMBL2803803 | 0.91 | FASN (0.40) | FASNALDH1A1 | |
| SCHEMBL2801670 | 0.90 | FASN (0.39) | FASNALDH1A1GPBAR1EGLN1 | |
| SCHEMBL2803140 | 0.88 | FASN (0.39) | FASNALDH1A1GPBAR1EGLN1SMN1; SMN2 | |
| SCHEMBL2800139 | 0.88 | FASN (0.42) | FASNALDH1A1PLATEGLN1SMN1; SMN2 | |
| SCHEMBL2801754 | 0.88 | ALDH1A1 (0.42) | ALDH1A1EGLN1SMN1; SMN2 | |
| SCHEMBL2800918 | 0.87 | KDM4E (0.42) | FASNALDH1A1SMN1; SMN2 | |
| SCHEMBL2803213 | 0.87 | NPC1 (0.40) | FASNALDH1A1 | |
| SCHEMBL2801081 | 0.87 | KDR (0.39) | FASNALDH1A1GPBAR1EGLN1 | |
| SCHEMBL2803186 | 0.87 | FASN (0.38) | FASNALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160008362-A1 | AGENT FOR PREVENTING AND/OR TREATING OCULAR INFLAMMATORY DISEASE | KYOWA HAKKO KIRIN CO., LTD. (JP) | 2016-01-14 | — | — | US | claimed |
| EP-2962692-A1 | AGENT FOR PREVENTING AND/OR TREATING OCULAR INFLAMMATORY DISEASE | Kyowa Hakko Kirin Co., Ltd. (JP) | 2016-01-06 | — | — | EP | claimed |
| US-8729264-B2 | Agent for prevention and/or treatment of skin diseases | KYOWA HAKKO KIRIN CO., LTD. (JP) | 2014-05-20 | — | — | US | claimed |
| US-20160008362-A1 | AGENT FOR PREVENTING AND/OR TREATING OCULAR INFLAMMATORY DISEASE | KYOWA HAKKO KIRIN CO., LTD. (JP) | 2016-01-14 | — | — | US | disclosed |
| EP-2962692-A1 | AGENT FOR PREVENTING AND/OR TREATING OCULAR INFLAMMATORY DISEASE | Kyowa Hakko Kirin Co., Ltd. (JP) | 2016-01-06 | — | — | EP | disclosed |
| EP-2206714-B1 | AGENT FOR PREVENTION AND/OR TREATMENT OF SKIN DISEASES | KYOWA HAKKO KIRIN CO LTD (JP) | 2015-01-21 | — | — | EP | disclosed |
| US-8729264-B2 | Agent for prevention and/or treatment of skin diseases | KYOWA HAKKO KIRIN CO., LTD. (JP) | 2014-05-20 | — | — | US | disclosed |
| US-20100256134-A1 | AGENT FOR PREVENTION AND/OR TREATMENT OF SKIN DISEASES | KYOWA HAKKO KIRIN CO., LTD. (JP) | 2010-10-07 | — | — | US | disclosed |
| EP-2206714-A1 | AGENT FOR PREVENTION AND/OR TREATMENT OF SKIN DISEASES | Kyowa Hakko Kirin Co., Ltd. (JP) | 2010-07-14 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160008362-A1 | AGENT FOR PREVENTING AND/OR TREATING OCULAR INFLAMMATORY DISEASE | NR0B1, NR2E3, NR0B2 | FASN 2967/4885ALDH1A1 1026/4885PLAT 4779/4885 |
| US-20100256134-A1 | AGENT FOR PREVENTION AND/OR TREATMENT OF SKIN DISEASES | TYR, CUTA, SERPINB1 | FASN 4286/4885ALDH1A1 243/4885PLAT 1506/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.