Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.42 |
| ▸ | SIRT3 | Q9NTG7 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | KDM4C | Q9H3R0 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | KDM6B | O15054 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KDM4A | O75164 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | F7 | P08709 | 1/20 | 0.37 |
| ▸ | F3 | P13726 | 1/20 | 0.37 |
| ▸ | SARM1 | Q6SZW1 | 1/20 | 0.37 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.37 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7263236 | 0.82 | KDM4C (0.48) | NAPRTTDP1SIRT3KDM4EMAPT | |
| SCHEMBL11290152 | 0.76 | TDP1 (0.49) | NAPRTTDP1SIRT3KDM4EMAPT | |
| SCHEMBL28021639 | 0.75 | KDM4C (0.58) | NAPRTTDP1SIRT3KDM4EMAPT | |
| SCHEMBL27598452 | 0.75 | BCAT2 (0.54) | TDP1KDM4EMAPTCYP1A2F7 | |
| SCHEMBL3326582 | 0.75 | AOC1 (0.57) | NAPRTTDP1KDM4EMAPTCYP1A2 | |
| SCHEMBL11459066 | 0.72 | NAPRT (0.47) | NAPRTTDP1KDM4EMAPTCYP1A2 | |
| SCHEMBL8746918 | 0.72 | NAPRT (0.47) | NAPRTTDP1SIRT3KDM4EMAPT | |
| SCHEMBL3443861 | 0.72 | NAPRT (0.47) | NAPRTKDM4EMAPTCYP1A2KDM4C | |
| SCHEMBL29091757 | 0.72 | LOXL2 (0.55) | NAPRTTDP1KDM4EMAPTCYP1A2 | |
| SCHEMBL27904192 | 0.72 | NAPRT (0.47) | NAPRTTDP1KDM4EMAPTCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102947292-B | nitrogen-containing heteroaryl compounds | HOFFMAN-LA ROCHE LTD. (CH) | 2015-08-19 | — | — | CN | disclosed |