Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 19/20 | 0.52 |
| ▸ | HTR2C | P28335 | 19/20 | 0.52 |
| ▸ | KCNH2 | Q12809 | 8/20 | 0.52 |
| ▸ | DRD2 | P14416 | 5/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27787732 | 0.84 | HTR2A (0.49) | HTR2AHTR2CKCNH2 | |
| SCHEMBL27731418 | 0.79 | LTA4H (0.52) | DRD2 | |
| SCHEMBL12891507 | 0.77 | HTR2A (0.62) | HTR2AHTR2CKCNH2DRD2 | |
| SCHEMBL2548388 | 0.77 | HTR2A (0.60) | HTR2AHTR2CKCNH2DRD2 | |
| SCHEMBL27787800 | 0.75 | HTR2A (0.56) | HTR2AHTR2CKCNH2DRD2 | |
| SCHEMBL27787706 | 0.73 | ALDH1A1 (0.51) | HTR2AHTR2CKCNH2 | |
| SCHEMBL27721167 | 0.72 | ALOX15 (0.45) | — | |
| SCHEMBL27600871 | 0.72 | BACE1 (0.34) | — | |
| SCHEMBL27495582 | 0.71 | HTR2A (0.58) | HTR2AHTR2CKCNH2DRD2 | |
| SCHEMBL5789253 | 0.71 | HTR2A (0.54) | HTR2AHTR2CKCNH2DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102838546-B | Pyrazole derivatives as modulators of 5-ht2a serotonin receptor useful for treatment of disorders related thereto | ARENA PHARM INC | 2015-07-15 | — | — | CN | disclosed |