Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 2/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.30 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 2/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | FDPS | P14324 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8380643 | 0.87 | DNM1 (0.39) | DNM1OPRM1ALDH1A1TDP1LMNA | |
| SCHEMBL8381370 | 0.79 | OPRM1 (0.42) | DNM1OPRM1ALDH1A1LMNATSHR | |
| SCHEMBL8381938 | 0.77 | LMNA (0.42) | DNM1OPRM1ALDH1A1LMNATSHR | |
| SCHEMBL1683581 | 0.77 | LMNA (0.42) | DNM1OPRM1ALDH1A1LMNATSHR | |
| SCHEMBL7854393 | 0.77 | LMNA (0.42) | DNM1OPRM1ALDH1A1LMNATSHR | |
| SCHEMBL8378801 | 0.77 | LMNA (0.42) | DNM1OPRM1ALDH1A1LMNATSHR | |
| SCHEMBL8381592 | 0.77 | LMNA (0.42) | DNM1OPRM1ALDH1A1LMNATSHR | |
| SCHEMBL9339601 | 0.77 | LMNA (0.42) | DNM1OPRM1ALDH1A1LMNATSHR | |
| SCHEMBL8379320 | 0.77 | LMNA (0.42) | DNM1OPRM1ALDH1A1LMNATSHR | |
| SCHEMBL27462068 | 0.77 | LMNA (0.42) | DNM1OPRM1ALDH1A1LMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104693211-A | Imidazole derivative as antiviral agent and pharmaceutical application thereof | NANJING MINGDE NEW DRUG RES AND DEV CO LTD | 2015-06-10 | — | — | CN | disclosed |