Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 5/20 | 0.33 |
| ▸ | CA2 | P00918 | 3/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | CA1 | P00915 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | FDPS | P14324 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8381370 | 0.92 | OPRM1 (0.42) | DNM1ALDH1A1TSHRLMNAFDPS | |
| SCHEMBL8381592 | 0.89 | LMNA (0.42) | DNM1ALDH1A1TSHRLMNAFDPS | |
| SCHEMBL7854393 | 0.89 | LMNA (0.42) | DNM1ALDH1A1TSHRLMNAFDPS | |
| SCHEMBL27462068 | 0.89 | LMNA (0.42) | DNM1ALDH1A1TSHRLMNAFDPS | |
| SCHEMBL8379320 | 0.89 | LMNA (0.42) | DNM1ALDH1A1TSHRLMNAFDPS | |
| SCHEMBL9339601 | 0.89 | LMNA (0.42) | DNM1ALDH1A1TSHRLMNAFDPS | |
| SCHEMBL8381938 | 0.89 | LMNA (0.42) | DNM1ALDH1A1TSHRLMNAFDPS | |
| SCHEMBL8378801 | 0.89 | LMNA (0.42) | DNM1ALDH1A1TSHRLMNAFDPS | |
| SCHEMBL1683581 | 0.89 | LMNA (0.42) | DNM1ALDH1A1TSHRLMNAFDPS | |
| SCHEMBL28022696 | 0.87 | DNM1 (0.35) | DNM1ALDH1A1TDP1TSHRCA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-56156247-A | — | — | None | — | — | JP | disclosed |
| CN-107129452-A | A kind of preparation method of blood lipid-lowering medicine ezetimibe and its key intermediate | 常州制药厂有限公司 | 2017-09-05 | — | — | CN | disclosed |
| EP-0767768-B1 | HALOALKYLATION PROCESS | ALBEMARLE CORP (US) | 1999-03-31 | — | — | EP | disclosed |
| EP-0767768-A1 | HALOALKYLATION PROCESS | ALBEMARLE CORPORATION (US) | 1997-04-16 | — | — | EP | disclosed |
| WO-1996000202-A1 | HALOALKYLATION PROCESS | ALBEMARLE CORPORATION (US) | 1996-01-04 | — | — | WO | disclosed |
| US-5475170-A | Haloalkylation process | ALBERMARLE CORPORATION (US) | 1995-12-12 | — | — | US | disclosed |
| US-5319150-A | Chloroalkylation of aromatic compounds | ALBEMARLE CORPORATION (US) | 1994-06-07 | — | — | US | disclosed |
| US-5136115-A | BROMOALKYLATION OF AROMATIC COMPOUNDS | ALBERMARLE CORPORATION | 1992-08-04 | — | — | US | disclosed |
| EP-0369728-A1 | Haloalkylation of aromatic compounds | ETHYL CORPORATION (US) | 1990-05-23 | — | — | EP | disclosed |
| JP-S56156247-A | BENZAMIDE DERIVATIVE AND HERBICIDE COMPRISING IT | HODOGAYA CHEM CO LTD | 1981-12-02 | — | — | JP | disclosed |
| US-4125552-A | FROM A HALIDE, AMMONIA, HYDROCARBYLAMINE, HYDROGEN SULFIDE AND SULFUR | DOW CORNING CORPORATION (US) | 1978-11-14 | — | — | US | disclosed |
| US-4082790-A | ORGANIC HALIDE, HYDROGEN SULFIDE, AMMONIA OR AMINE, POLAR SOLVENT | DOW CORNING CORPORATION (US) | 1978-04-04 | — | — | US | disclosed |