Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 7/20 | 0.51 |
| ▸ | SCD | O00767 | 2/20 | 0.51 |
| ▸ | FADS1 | O60427 | 1/20 | 0.51 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.50 |
| ▸ | PTPRC | P08575 | 1/20 | 0.49 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.49 |
| ▸ | JAK2 | O60674 | 2/20 | 0.47 |
| ▸ | FAAH | O00519 | 1/20 | 0.46 |
| ▸ | PARP1 | P09874 | 1/20 | 0.46 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.45 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.45 |
| ▸ | JAK3 | P52333 | 1/20 | 0.44 |
| ▸ | BRD4 | O60885 | 1/20 | 0.44 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30604310 | 0.85 | HSD17B1 (0.47) | PTGS2KAT6AJAK2FAAHPARP1 | |
| SCHEMBL4159024 | 0.83 | BRD4 (0.55) | SCDKAT6APTPRCPTPN1NR1H2 | |
| SCHEMBL308372 | 0.83 | KAT6A (0.53) | PTGS2KAT6APTPRCPTPN1BRD4 | |
| SCHEMBL14161390 | 0.83 | CA1 (0.55) | PTGS2SCDKAT6APTPRCPTPN1 | |
| SCHEMBL14120596 | 0.83 | KAT6A (0.50) | PTGS2SCDFADS1KAT6APTPRC | |
| SCHEMBL17175626 | 0.81 | FAAH (0.51) | PTGS2KAT6AJAK2FAAHPARP1 | |
| SCHEMBL9206986 | 0.80 | PTGS2 (0.73) | PTGS2SCDFADS1 | |
| SCHEMBL25680126 | 0.80 | JAK2 (0.45) | PTGS2JAK2PARP1NR1H2NR1H3 | |
| SCHEMBL17165959 | 0.80 | FAAH (0.42) | PTGS2JAK2FAAHPARP1NR1H2 | |
| SCHEMBL28022794 | 0.79 | NR1H2 (0.52) | PTGS2SCDKAT6AJAK2NR1H2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105102449-A | Antiviral compounds | HOFFMANN LA ROCHE | 2015-11-25 | — | — | CN | claimed |
| CN-103443082-A | Prodrugs of LXR modulating imidazole derivatives | BRISTOL MYERS SQUIBB CO | 2013-12-11 | — | — | CN | disclosed |