Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 3/20 | 0.55 |
| ▸ | SCD | O00767 | 1/20 | 0.53 |
| ▸ | FLT1 | P17948 | 2/20 | 0.49 |
| ▸ | FLT4 | P35916 | 2/20 | 0.49 |
| ▸ | KDR | P35968 | 2/20 | 0.49 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.48 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.48 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.47 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 5/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 5/20 | 0.46 |
| ▸ | PTPRC | P08575 | 1/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.45 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.45 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.45 |
| ▸ | GRIA4 | P48058 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28022700 | 0.83 | PTGS2 (0.51) | BRD4SCDKAT6ANR1H2NR1H3 | |
| SCHEMBL308372 | 0.80 | KAT6A (0.53) | BRD4KAT6APTPRCPTPN1FFAR1 | |
| SCHEMBL14161390 | 0.80 | CA1 (0.55) | BRD4SCDKAT6APTPRCPTPN1 | |
| SCHEMBL14120596 | 0.80 | KAT6A (0.50) | SCDKAT6APTPRCPTPN1FFAR1 | |
| SCHEMBL4629461 | 0.79 | PSIP1 (0.65) | BRD4FLT1FLT4KDRPSIP1 | |
| SCHEMBL10305004 | 0.77 | BRD4 (0.58) | BRD4PSIP1NR1H2NR1H3CYP1A2 | |
| SCHEMBL29628986 | 0.74 | PTPRC (0.55) | KAT6APTPRCPTPN1FFAR1 | |
| SCHEMBL12856837 | 0.74 | PTPRC (0.55) | KAT6APTPRCPTPN1FFAR1 | |
| SCHEMBL17263850 | 0.74 | PSIP1 (0.68) | BRD4FLT1FLT4KDRPSIP1 | |
| SCHEMBL777610 | 0.73 | PSIP1 (0.56) | BRD4FLT1FLT4KDRPSIP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090227603-A1 | LEUKOTRIENE B4 INHIBITORS | DOMINIQUE ROMYR | 2009-09-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090227603-A1 | LEUKOTRIENE B4 INHIBITORS | LTB4R2, LTB4R, LTC4S | BRD4 2322/4885SCD 256/4885FLT1 3730/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.