Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 3/20 | 0.54 |
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | FFAR1 | O14842 | 4/20 | 0.51 |
| ▸ | FAAH | O00519 | 1/20 | 0.51 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.50 |
| ▸ | BRS3 | P32247 | 1/20 | 0.49 |
| ▸ | CDK4 | P11802 | 1/20 | 0.48 |
| ▸ | CCND1 | P24385 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6513919 | 0.83 | KDM4E (0.54) | RAB9AGAAKDM4ECDK4CCND1 | |
| SCHEMBL28023427 | 0.83 | GPR52 (0.56) | RAB9AGAANPC1FFAR1ALDH1A1 | |
| SCHEMBL496484 | 0.82 | KDM4E (0.62) | HCAR2RAB9AGAAKDM4EALDH1A1 | |
| SCHEMBL28022707 | 0.81 | HCAR2 (0.52) | HCAR2RAB9AGAAFFAR1FAAH | |
| SCHEMBL8887143 | 0.80 | GAA (0.59) | GAAKDM4ECDK4CCND1ALDH1A1 | |
| SCHEMBL1515816 | 0.79 | GAA (0.62) | RAB9AGAAKDM4ENPC1CDK4 | |
| SCHEMBL28023330 | 0.78 | NPC1 (0.54) | RAB9ANPC1FFAR1FAAHKMT2A | |
| SCHEMBL30285198 | 0.77 | SLC6A3 (0.66) | GAAKDM4ECDK4CCND1ALDH1A1 | |
| SCHEMBL4709256 | 0.77 | BCAT2 (0.59) | RAB9AGAAKDM4ENPC1CDK4 | |
| SCHEMBL7894667 | 0.77 | GAA (0.57) | GAAKDM4ECDK4CCND1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104860803-B | Biphenyl ketonic compound and its preparation method and application | 暨南大学 | 2016-11-30 | — | — | CN | disclosed |
| CN-104860803-A | Biphenyl compound and preparation method and application thereof | UNIV JINAN | 2015-08-26 | — | — | CN | disclosed |