Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 2/20 | 0.41 |
| ▸ | TACR1 | P25103 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | CHAT | P28329 | 1/20 | 0.36 |
| ▸ | SNCA | P37840 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.36 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.36 |
| ▸ | TTR | P02766 | 2/20 | 0.36 |
| ▸ | FABP4 | P15090 | 1/20 | 0.36 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.36 |
| ▸ | CDK2 | P24941 | 1/20 | 0.36 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | HNF4A | P41235 | 1/20 | 0.35 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.35 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28160333 | 0.83 | PTGS2 (0.47) | TACR1PTGS2HPGDHSD17B10 | |
| SCHEMBL1069769 | 0.83 | PTGES2 (0.42) | PTGS2 | |
| SCHEMBL28022909 | 0.80 | PTPN1 (0.35) | PTPN1TACR1ALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL29743050 | 0.78 | CASP1 (0.47) | ALDH1A1CHATSNCACASP1PTGS2 | |
| SCHEMBL232659 | 0.78 | CASP1 (0.47) | ALDH1A1CHATSNCACASP1PTGS2 | |
| SCHEMBL4801781 | 0.77 | KAT6A (0.46) | PTPN1ALDH1A1CHATSNCACASP1 | |
| SCHEMBL392931 | 0.77 | TSHR (0.41) | ALDH1A1CHATSNCACASP1PTGS2 | |
| SCHEMBL30166530 | 0.77 | TSHR (0.41) | ALDH1A1CHATSNCACASP1PTGS2 | |
| SCHEMBL28934633 | 0.76 | CASP1 (0.46) | ALDH1A1CHATSNCACASP1PTGS2 | |
| Lithium SCHEMBL3173875 | 0.76 | CASP1 (0.46) | ALDH1A1CHATSNCACASP1PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105102449-B | Antiviral compound | 豪夫迈·罗氏有限公司 | 2017-06-13 | — | — | CN | disclosed |
| CN-105102449-A | Antiviral compounds | HOFFMANN LA ROCHE | 2015-11-25 | — | — | CN | disclosed |