Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.33 |
| ▸ | MAPT | P10636 | 4/20 | 0.33 |
| ▸ | POLB | P06746 | 3/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 3/20 | 0.32 |
| ▸ | CA9 | Q16790 | 3/20 | 0.32 |
| ▸ | CFD | P00746 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.31 |
| ▸ | PKM | P14618 | 3/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7499320 | 0.81 | ALDH1A1 (0.49) | ALDH1A1MAPTPOLBPTGS2SMN1; SMN2 | |
| SCHEMBL27858874 | 0.80 | ALDH1A1 (0.41) | ALDH1A1MAPTPOLBPTGS2MEN1 | |
| SCHEMBL27472113 | 0.79 | ALDH1A1 (0.35) | ALDH1A1MAPTPOLBPTGS2MEN1 | |
| SCHEMBL17077645 | 0.79 | CYP2E1 (0.35) | ALDH1A1MAPTPOLBMEN1KMT2A | |
| SCHEMBL28057100 | 0.75 | ALDH1A1 (0.40) | ALDH1A1MAPTPOLBMEN1KMT2A | |
| SCHEMBL27373829 | 0.75 | PTGS2 (0.38) | ALDH1A1MAPTPOLBPTGS2MEN1 | |
| SCHEMBL27488370 | 0.73 | HTT (0.42) | ALDH1A1MAPTPOLBKMT2ASMN1; SMN2 | |
| SCHEMBL27487969 | 0.72 | KMT2A (0.44) | ALDH1A1MAPTPOLBMEN1KMT2A | |
| SCHEMBL21662447 | 0.71 | ELANE (0.45) | ALDH1A1MAPTPOLBMEN1KMT2A | |
| SCHEMBL6754107 | 0.70 | LMNA (0.43) | ALDH1A1MAPTPOLBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104822678-A | Compounds having muscarinic receptor antagonist and beta2 adrenergic receptor agonist activity | CHIESI FARMA SPA | 2015-08-05 | — | — | CN | disclosed |