Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.38 |
| ▸ | GAA | P10253 | 3/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | GLA | P06280 | 2/20 | 0.38 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.38 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.38 |
| ▸ | GFER | P55789 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 4/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17581887 | 0.82 | HSP90AB1 (0.50) | ALDH1A1HSD17B10KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL27858874 | 0.79 | ALDH1A1 (0.41) | ALDH1A1HSD17B10KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL27472113 | 0.77 | ALDH1A1 (0.35) | ALDH1A1HSD17B10KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL17077645 | 0.77 | CYP2E1 (0.35) | ALDH1A1HSD17B10KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL10209863 | 0.76 | HTT (0.51) | ALDH1A1HSD17B10KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL10174351 | 0.75 | ALOX5 (0.46) | ALDH1A1HSD17B10KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL17581889 | 0.75 | HSP90AB1 (0.44) | ALDH1A1HSD17B10KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL21366512 | 0.75 | MITF (0.42) | ALDH1A1HSD17B10KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL28023102 | 0.75 | ALDH1A1 (0.33) | ALDH1A1HSD17B10KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL23395635 | 0.74 | NPC1 (0.55) | ALDH1A1HSD17B10KMT2AMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102574801-B | Substituted aminopropionic acid derivatives as enkephalinase inhibitors | NOVARTIS AG (CH) | 2016-04-27 | — | — | CN | disclosed |
| CN-103896796-B | As the alanine derivatives of the replacement of enkephalinase inhibitor | NOVARTIS AG (CH) | 2016-04-27 | — | — | CN | disclosed |