Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16084093 | 0.85 | USP2 (0.33) | — | |
| Tert-Butyl Formate SCHEMBL28023820 | 0.81 | CYP46A1 (0.40) | — | |
| Tert-Butyl Formate SCHEMBL28313659 | 0.78 | OPRL1 (0.42) | TDP1 | |
| Tert-Butyl Formate SCHEMBL28818068 | 0.76 | DRD2 (0.40) | TDP1 | |
| Tert-Butyl Formate SCHEMBL28797112 | 0.75 | OPRM1 (0.33) | TDP1 | |
| Tert-Butyl Formate SCHEMBL28023816 | 0.75 | FDPS (0.37) | — | |
| Tert-Butyl Formate SCHEMBL28106914 | 0.74 | TDP1 (0.42) | TDP1 | |
| Tert-Butyl Formate SCHEMBL28818064 | 0.73 | FPR2 (0.43) | — | |
| Tert-Butyl Formate SCHEMBL27814649 | 0.73 | TDP1 (0.48) | TDP1 | |
| SCHEMBL6765291 | 0.73 | USP2 (0.45) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105121425-A | Therapeutic compounds and compositions | AGIOS PHARMACEUTICALS INC | 2015-12-02 | — | — | CN | disclosed |