SCHEMBL2802347

SCHEMBL2802347

COC(=O)c1ccccc1CCl

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.62
LMNA P02545 2/20 0.62
TSHR P16473 1/20 0.55
HSD17B10 Q99714 2/20 0.53
CFTR P13569 1/20 0.53
KDM4E B2RXH2 2/20 0.52
POLB P06746 2/20 0.52
ATM Q13315 1/20 0.52
KMT2A Q03164 1/20 0.51
HIF1A Q16665 1/20 0.51
SLC6A3 Q01959 2/20 0.49
GLA P06280 1/20 0.49
SLC6A4 P31645 1/20 0.49
HTT P42858 1/20 0.48
CA1 P00915 1/20 0.47
CA2 P00918 1/20 0.47
CA5A P35218 1/20 0.47
CA9 Q16790 1/20 0.47
MAPT P10636 1/20 0.47
ALOX15 P16050 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27881005 0.93 LMNA (0.55) ALDH1A1LMNATSHRHSD17B10CFTR
SCHEMBL1920110 0.85 ALDH1A1 (0.68) ALDH1A1LMNATSHRHSD17B10CFTR
SCHEMBL10360804 0.84 ALDH1A1 (0.77) ALDH1A1LMNATSHRHSD17B10CFTR
SCHEMBL8731468 0.84 ALDH1A1 (0.43) ALDH1A1LMNATSHRKDM4EKMT2A
SCHEMBL70322 0.84 ALDH1A1 (0.66) ALDH1A1LMNATSHRHSD17B10CFTR
SCHEMBL156281 0.84 ALDH1A1 (0.66) ALDH1A1LMNATSHRHSD17B10CFTR
SCHEMBL6046682 0.84 ALDH1A1 (0.49) ALDH1A1LMNATSHRHSD17B10CFTR
SCHEMBL7715910 0.84 ALDH1A1 (0.49) ALDH1A1LMNATSHRHSD17B10CFTR
SCHEMBL2093835 0.82 ALDH1A1 (0.64) ALDH1A1LMNATSHRHSD17B10CFTR
SCHEMBL5345862 0.82 ALDH1A1 (0.64) ALDH1A1LMNATSHRHSD17B10CFTR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 210 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117924217-A 5-HTT/HDAC dual inhibitor and preparation method and application thereof 杭州师范大学 2024-04-26 CN claimed
CN-116514687-A Method for synthesizing methyl orthoformate benzyl sulfonamide 河北允升精细化工有限公司 2023-08-01 CN claimed
CN-111606829-B Production method of o-methyl formate benzyl sulfonamide 淄博腾煜化工工程有限公司 2022-07-08 CN claimed
CN-113563236-A Synthesis method of o-methyl formate benzylsulfonamide 石家庄圣泰化工有限公司 2021-10-29 CN claimed
CN-111606829-A Production method of o-methyl formate benzyl sulfonamide 淄博腾煜化工工程有限公司 2020-09-01 CN claimed
CN-104262318-B A kind of preparation method of Olopatadine hydrochloride HEBEI RENHE YIKANG PHARMACEUTICAL CO., LTD. (CN) 2016-02-17 CN claimed
CN-104262318-A Method for preparing olopatadine hydrochloride SHIJIAZHUANG CHUANGJIAN PHARMACEUTICAL TECHNOLOGY CO LTD 2015-01-07 CN claimed
EP-2058294-B1 METHOD FOR PRODUCING 2-(4-METHOXYCARBONYLMETHYLPHENOXYMETHYL)BENZOIC ACID METHYL ESTER SUMITOMO CHEMICAL CO (JP) 2013-01-02 EP claimed
CN-102584709-A Improved process for preparing aryl imidazole aldehyde serving as eprosartan intermediate ZHEJIANG HUAHAI PHARM CO LTD 2012-07-18 CN claimed
CN-102250238-A Method for synthesizing swainsonine antigen UNIV NORTHWEST A&F 2011-11-23 CN claimed
EP-2181989-A2 Process for the preparation of olopatadine Sumitomo Chemical Company, Limited (JP) 2010-05-05 EP claimed
CN-101516865-A Tertiary alkyl ester of oxodibenzoxepin acetic acid SUMITOMO CHEMICAL CO (JP) 2009-08-26 CN claimed
CN-101506141-A Methyl 2- (4-methoxycarbonylmethylphenoxymethyl) benzoate and process for producing the same SUMITOMO CHEMICAL CO (JP) 2009-08-12 CN claimed
EP-2072507-A1 TERTIARY ALKYL ESTER OF OXODIBENZOXEPIN ACETIC ACID Sumitomo Chemical Company, Limited (JP) 2009-06-24 EP claimed
CN-101434545-A Method for preparing methyl p-chloromethyl benzoate WUHAN YOUJI IND COMPANY LTD (CN) 2009-05-20 CN claimed
EP-2058294-A1 2-(4-METHOXYCARBONYLMETHYLPHENOXYMETHYL)BENZOIC ACID METHYL ESTER AND METHOD FOR PRODUCING THE SAME Sumitomo Chemical Company, Limited (JP) 2009-05-13 EP claimed
CN-117551011-B Preparation method of benzylamine compound SHANDONG KANGQIAO BIO-TECHNOLOGY Co.,Ltd. (CN) 2026-05-29 CN disclosed
CN-116143637-B Organic compound, organic electroluminescent device and electronic device comprising the same 陕西莱特光电材料股份有限公司 2025-05-02 CN disclosed
US-4053501-A PLANT GROWTH REGULATORS MONSANTO COMPANY (US) 1977-10-11 US disclosed
US-4022897-A 4H-PYRIDO(1,2-A) PYRIMIDIN-4-ONE DERIVATIVES E. R. SQUIBB & SONS, INC. (US) 1977-05-10 US disclosed