Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRP | O00591 | 3/20 | 0.41 |
| ▸ | GABRD | O14764 | 3/20 | 0.41 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.41 |
| ▸ | GABRB1 | P18505 | 3/20 | 0.41 |
| ▸ | GABRG2 | P18507 | 3/20 | 0.41 |
| ▸ | GABRB3 | P28472 | 3/20 | 0.41 |
| ▸ | GABRA5 | P31644 | 3/20 | 0.41 |
| ▸ | GABRA3 | P34903 | 3/20 | 0.41 |
| ▸ | GABRA2 | P47869 | 3/20 | 0.41 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.41 |
| ▸ | GABRA4 | P48169 | 3/20 | 0.41 |
| ▸ | GABRE | P78334 | 3/20 | 0.41 |
| ▸ | GABRA6 | Q16445 | 3/20 | 0.41 |
| ▸ | GABRG1 | Q8N1C3 | 3/20 | 0.41 |
| ▸ | GABRG3 | Q99928 | 3/20 | 0.41 |
| ▸ | GABRQ | Q9UN88 | 3/20 | 0.41 |
| ▸ | PTPRC | P08575 | 1/20 | 0.36 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | PTPRA | P18433 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23531201 | 0.83 | ALDH1A1 (0.36) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL30280779 | 0.83 | ALDH1A1 (0.36) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL28754887 | 0.82 | ALDH1A1 (0.46) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL13928916 | 0.81 | GABRP (0.39) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL25922204 | 0.80 | DHFR (0.35) | — | |
| SCHEMBL29240829 | 0.79 | GABRP (0.47) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL30280735 | 0.78 | MAPT (0.37) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL28876061 | 0.78 | MAPT (0.37) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| Ammonia Solution, Strong SCHEMBL29170068 | 0.78 | GABRP (0.46) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL6206460 | 0.78 | ALDH1A1 (0.44) | GABRPGABRDGABRA1GABRB1GABRG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110177551-A | HETEROCYCLIC MODULATORS OF LIPID SYNTHESIS | 3-V生物科学股份有限公司 | 2019-08-27 | — | — | CN | disclosed |
| CN-105001225-B | The heterocyclic modulators of lipid synthesis | 3-V 生物科学公司 | 2018-04-06 | — | — | CN | disclosed |
| CN-105001225-A | Heterocyclic modulators of lipid synthesis | 3 V BIOSCIENCES INC | 2015-10-28 | — | — | CN | disclosed |
| CN-103561576-B | Heterocyclic modulators of lipid synthesis | 3 V BIOSCIENCES INC | 2015-07-22 | — | — | CN | disclosed |