Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 8/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28023643 | 0.86 | HSD11B1 (0.45) | HSD11B1TP53TSHRPOLBMAPT | |
| SCHEMBL28321813 | 0.80 | LMNA (0.49) | TP53TSHRMAPTSMN1; SMN2 | |
| SCHEMBL28023644 | 0.77 | TSHR (0.40) | HSD11B1TP53TSHRPOLBMAPT | |
| SCHEMBL31544794 | 0.76 | TSHR (0.44) | TP53TSHRPOLBMAPTSMN1; SMN2 | |
| SCHEMBL28406543 | 0.75 | ALDH1A1 (0.49) | TP53TSHR | |
| SCHEMBL83439 | 0.74 | TSHR (0.47) | TP53TSHRPOLBSMN1; SMN2 | |
| SCHEMBL28023023 | 0.73 | TSHR (0.46) | HSD11B1TP53TSHRMAPTSMN1; SMN2 | |
| SCHEMBL14336043 | 0.70 | TDP1 (0.59) | HSD11B1POLBMAPTCA12CA9 | |
| SCHEMBL28023026 | 0.69 | TSHR (0.44) | HSD11B1TP53TSHRMAPTSMN1; SMN2 | |
| SCHEMBL27948832 | 0.69 | MEN1 (0.53) | HSD11B1TP53TSHRPOLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103509135-B | Olefin polymerization catalyst component, preparation method and application thereof | CHINA PETROLEUM & CHEMICAL | 2015-07-22 | — | — | CN | disclosed |