Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.42 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.41 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 5/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | RAB9A | P51151 | 4/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | HTT | P42858 | 3/20 | 0.40 |
| ▸ | F2 | P00734 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28023026 | 0.81 | TSHR (0.44) | TSHRTP53HSD11B1MAPTSMN1; SMN2 | |
| SCHEMBL28023655 | 0.79 | TSHR (0.50) | TSHRTP53HSD11B1MAPTSMN1; SMN2 | |
| SCHEMBL28023644 | 0.77 | TSHR (0.40) | TSHRTP53HSD11B1MAPTSMN1; SMN2 | |
| SCHEMBL28023039 | 0.76 | TSHR (0.47) | TSHRTP53HSD11B1SMN1; SMN2PDCD1 | |
| SCHEMBL28023643 | 0.75 | HSD11B1 (0.45) | TSHRTP53HSD11B1MAPTSMN1; SMN2 | |
| SCHEMBL28023628 | 0.74 | LMNA (0.46) | TSHRTP53SMN1; SMN2PDCD1CD274 | |
| SCHEMBL65543 | 0.73 | TSHR (0.55) | TSHRTP53MAPTSMN1; SMN2PDCD1 | |
| SCHEMBL28023656 | 0.73 | HSD11B1 (0.47) | TSHRTP53HSD11B1MAPTSMN1; SMN2 | |
| SCHEMBL6660758 | 0.72 | TSHR (0.63) | TSHRTP53MAPTSMN1; SMN2PDCD1 | |
| SCHEMBL16046613 | 0.70 | TSHR (0.47) | TSHRTP53HSD11B1MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103509135-B | Olefin polymerization catalyst component, preparation method and application thereof | CHINA PETROLEUM & CHEMICAL | 2015-07-22 | — | — | CN | disclosed |