SCHEMBL28023658

SCHEMBL28023658

CCC(N(C)C)S(=O)(=O)c1cccc(OC(=O)c2ccccc2)c1

nearest known ligand 0.48

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.48
SMN1; SMN2 Q16637 1/20 0.48
KMT2A Q03164 8/20 0.43
ALDH1A1 P00352 3/20 0.43
PKM P14618 1/20 0.43
MEN1 O00255 2/20 0.42
TDP1 Q9NUW8 1/20 0.42
HSD11B1 P28845 1/20 0.40
KAT6A Q92794 2/20 0.40
HSP90AA1 P07900 1/20 0.40
KDM4E B2RXH2 1/20 0.39
GLA P06280 1/20 0.39
GAA P10253 1/20 0.39
HPGD P15428 1/20 0.39
DUT P33316 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28023647 0.91 MAPT (0.46) MAPTSMN1; SMN2KMT2AALDH1A1PKM
SCHEMBL28023028 0.77 KMT2A (0.43) MAPTSMN1; SMN2KMT2AALDH1A1PKM
SCHEMBL27933091 0.76 HSD11B1 (0.47) MAPTSMN1; SMN2KMT2AALDH1A1MEN1
SCHEMBL28023032 0.76 PSIP1 (0.47) MAPTSMN1; SMN2ALDH1A1TDP1HSD11B1
SCHEMBL28023653 0.74 KAT6A (0.46) MAPTSMN1; SMN2KMT2AALDH1A1MEN1
SCHEMBL27979378 0.74 CA2 (0.53) MAPTSMN1; SMN2KMT2AALDH1A1MEN1
SCHEMBL1409659 0.74 KMT2A (0.53) MAPTSMN1; SMN2KMT2AALDH1A1MEN1
SCHEMBL12133492 0.73 KMT2A (0.49) MAPTKMT2AALDH1A1MEN1TDP1
SCHEMBL9867004 0.73 KAT6A (0.51) MAPTSMN1; SMN2KMT2AALDH1A1MEN1
SCHEMBL9987065 0.71 KMT2A (0.51) MAPTKMT2AALDH1A1MEN1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103509135-B Olefin polymerization catalyst component, preparation method and application thereof CHINA PETROLEUM & CHEMICAL 2015-07-22 CN disclosed