Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KAT6A | Q92794 | 3/20 | 0.51 |
| ▸ | HTR2B | P41595 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | CRHBP | P24387 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | DUT | P33316 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.43 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16000127 | 0.80 | PGR (0.56) | KAT6AALDH1A1 | |
| SCHEMBL9568752 | 0.80 | HTR2B (0.44) | KAT6AHTR2BALDH1A1LMNA | |
| SCHEMBL13543487 | 0.80 | CA1 (0.62) | HTR2BKMT2AHDAC8HDAC6PTPN1 | |
| SCHEMBL3246077 | 0.79 | HTR2B (0.43) | KAT6AHTR2BALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL27979378 | 0.77 | CA2 (0.53) | KMT2AMAPTALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL1409659 | 0.77 | KMT2A (0.53) | KMT2AMAPTALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL12376754 | 0.77 | KEAP1 (0.57) | KAT6AALDH1A1LMNA | |
| SCHEMBL12376737 | 0.76 | HTR2B (0.62) | HTR2BKMT2AMAPTALDH1A1LMNA | |
| SCHEMBL13674329 | 0.75 | KMT2A (0.57) | KAT6AKMT2AMAPTALDH1A1LMNA | |
| SCHEMBL28097814 | 0.75 | ALDH1A1 (0.43) | HTR2BALDH1A1LMNAHDAC8HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4987141-A | DERIVATIVES OF BENZENE OR PYRIDINE HAVING SULFONATE AND SULFENYL, SULFONIMIDE OR SULFONAMIDE GROUPS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1991-01-22 | — | — | US | disclosed |