Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.45 |
| ▸ | KIF11 | P52732 | 6/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.42 |
| ▸ | RELA | Q04206 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.40 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.40 |
| ▸ | APP | P05067 | 1/20 | 0.40 |
| ▸ | LTA4H | P09960 | 1/20 | 0.40 |
| ▸ | CA4 | P22748 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28023866 | 0.82 | HPGD (0.41) | KMT2AKIF11ALDH1A1NPC1RAB9A | |
| SCHEMBL28820996 | 0.81 | L3MBTL1 (0.40) | KMT2AKIF11ALDH1A1NPC1RAB9A | |
| SCHEMBL28013242 | 0.81 | ALDH1A1 (0.45) | KMT2AKIF11ALDH1A1NPC1RAB9A | |
| SCHEMBL28013823 | 0.79 | MAPT (0.46) | KMT2AKIF11ALDH1A1NPC1RAB9A | |
| SCHEMBL30887388 | 0.76 | KMT2A (0.62) | KMT2AAOC3KIF11SMN1; SMN2KCNH2 | |
| SCHEMBL30863776 | 0.74 | ALDH1A1 (0.46) | KMT2AKIF11ALDH1A1NPC1RAB9A | |
| SCHEMBL28076980 | 0.72 | CA4 (0.52) | KMT2AAOC3KIF11SMN1; SMN2KCNH2 | |
| SCHEMBL9906174 | 0.72 | CA4 (0.52) | KMT2AAOC3KIF11SMN1; SMN2KCNH2 | |
| SCHEMBL30863784 | 0.72 | SMN1; SMN2 (0.44) | KMT2AKIF11ALDH1A1NPC1RAB9A | |
| SCHEMBL28013332 | 0.71 | MTNR1A (0.46) | KMT2AALDH1A1NPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104744325-B | A kind of Alpha-hydroxy thioether and preparation method and application | 中国人民大学 | 2016-08-17 | — | — | CN | disclosed |
| CN-104744325-A | Alpha- hydroxysulfide and preparation method and application thereof | PEOPLES UNIV CHINA | 2015-07-01 | — | — | CN | disclosed |