Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | KIF11 | P52732 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | MLYCD | O95822 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28820996 | 0.85 | L3MBTL1 (0.40) | HPGDALDH1A1CYP2C19KMT2AMEN1 | |
| SCHEMBL28023865 | 0.82 | KMT2A (0.51) | ALDH1A1KMT2ALMNAMAPTHTT | |
| SCHEMBL28013839 | 0.79 | HPGD (0.44) | HPGDALDH1A1CYP2C19CYP1A2CYP3A4 | |
| SCHEMBL28023321 | 0.78 | LMNA (0.42) | ALDH1A1CYP2C19KMT2AMEN1LMNA | |
| SCHEMBL28013245 | 0.76 | KMT2A (0.45) | HPGDALDH1A1CYP2C19CYP1A2CYP3A4 | |
| SCHEMBL28013236 | 0.76 | ALDH1A1 (0.41) | HPGDALDH1A1CYP2C19CYP1A2CYP3A4 | |
| SCHEMBL28023320 | 0.74 | PIN1 (0.42) | HPGDALDH1A1CYP2C19CYP1A2CYP3A4 | |
| SCHEMBL508028 | 0.73 | HPGD (0.44) | HPGDALDH1A1CYP2C19CYP1A2CYP3A4 | |
| SCHEMBL11099727 | 0.72 | POLB (0.46) | ALDH1A1CYP2C19CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL28823227 | 0.72 | MLYCD (0.47) | HPGDALDH1A1CYP2C19CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104744325-B | A kind of Alpha-hydroxy thioether and preparation method and application | 中国人民大学 | 2016-08-17 | — | — | CN | disclosed |
| CN-104744325-A | Alpha- hydroxysulfide and preparation method and application thereof | PEOPLES UNIV CHINA | 2015-07-01 | — | — | CN | disclosed |