Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 1/20 | 0.46 |
| ▸ | MMP13 | P45452 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28367809 | 0.79 | SIGMAR1 (0.47) | MMP1MMP13KDM4ESIGMAR1SMN1; SMN2 | |
| SCHEMBL28808984 | 0.76 | ACP1 (0.44) | KDM4EHRH3SMN1; SMN2ALDH1A1 | |
| SCHEMBL2706345 | 0.71 | MEN1 (0.46) | SIGMAR1ALDH1A1 | |
| SCHEMBL23464746 | 0.71 | MEN1 (0.46) | SIGMAR1ALDH1A1 | |
| SCHEMBL203039 | 0.71 | MEN1 (0.46) | SIGMAR1ALDH1A1 | |
| SCHEMBL23540940 | 0.70 | SIGMAR1 (0.49) | MMP1MMP13KDM4ESIGMAR1POLB | |
| SCHEMBL15532870 | 0.70 | S1PR5 (0.69) | KDM4ESIGMAR1 | |
| SCHEMBL2918073 | 0.69 | SIGMAR1 (0.57) | KDM4ESIGMAR1POLBSMN1; SMN2ALDH1A1 | |
| SCHEMBL5191850 | 0.68 | LTA4H (0.49) | KDM4ESIGMAR1POLBPKMHRH3 | |
| SCHEMBL23415558 | 0.68 | S1PR5 (0.53) | SIGMAR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107922347-A | New imide derivative and its purposes as medicine | 田边三菱制药株式会社 | 2018-04-17 | — | — | CN | disclosed |
| CN-102971291-B | Novel amide derivative and use thereof as medicine | MITSUBISHI TANABE PHARMA CORP | 2015-07-22 | — | — | CN | disclosed |