Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | DRD4 | P21917 | 4/20 | 0.45 |
| ▸ | CMA1 | P23946 | 1/20 | 0.43 |
| ▸ | PTGIR | P43119 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | HRH2 | P25021 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | GSK3A | P49840 | 1/20 | 0.41 |
| ▸ | GSK3B | P49841 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | MMP1 | P03956 | 1/20 | 0.41 |
| ▸ | MMP13 | P45452 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28364462 | 0.82 | ALDH1A1 (0.42) | SIGMAR1DRD4KDM4EGAAMEN1 | |
| SCHEMBL28023906 | 0.79 | MMP1 (0.46) | SIGMAR1SMN1; SMN2KDM4EALDH1A1MMP1 | |
| SCHEMBL28368556 | 0.74 | SIGMAR1 (0.50) | SIGMAR1MAPTKDM4EGAAALDH1A1 | |
| SCHEMBL493570 | 0.72 | SIGMAR1 (0.58) | SIGMAR1SMN1; SMN2PTGIRMEN1KMT2A | |
| SCHEMBL4771166 | 0.72 | SIGMAR1 (0.58) | SIGMAR1SMN1; SMN2DRD4HRH2 | |
| SCHEMBL14198701 | 0.71 | KDM4E (0.57) | SIGMAR1DRD4PTGIRHRH2KDM4E | |
| SCHEMBL28364395 | 0.70 | CMA1 (0.44) | SIGMAR1CMA1MAPTHRH2KDM4E | |
| SCHEMBL22674287 | 0.70 | DRD4 (0.49) | SIGMAR1SMN1; SMN2DRD4PTGIRHRH2 | |
| SCHEMBL22674824 | 0.70 | DRD4 (0.49) | SIGMAR1SMN1; SMN2DRD4PTGIRHRH2 | |
| SCHEMBL22674472 | 0.70 | DRD4 (0.49) | SIGMAR1SMN1; SMN2DRD4PTGIRHRH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107216315-B | Flavone imidazole compound and preparation method thereof | 盐城师范学院 | 2020-03-17 | — | — | CN | claimed |
| CN-107216315-B | Flavone imidazole compound and preparation method thereof | 盐城师范学院 | 2020-03-17 | — | — | CN | disclosed |